description
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product line
MISSION®
form
lyophilized powder
esiRNA cDNA target sequence
TGGAGGTTTTGCTGCTTTCTCTGCTGCGATTGATTATTACCTCCGGTGAGAGTAATTGCCTGCAGGGAAGGATGATGCCAGCCCCGGATCCGGGCTGCTCTCTGGAGGACAGTTTCTGTACCACACCAGGGCCTTGCTTCAGGGCCTGAAGACATTCATTTTCCCTCATGTCGTTGGTATTCTGAGGGAGCTGCCTGGCTTCTCTGCCTCCAGCCTTTGGGGTAGCCACACTTTGCTGCTCCTGGACTCCAGCCAGCCTTCACAGAGGACGTCCCGTGCCAGATTCTCTCACAGCAGATCGGGAGACAGGATGTTGACATATAGGAATTCAGCTCCACAAAGCTTCAGGCCTGACCACAGCTGGCCCTCTAGGTTGTTTGGTGTTGTGGGCACAGAGGTGACAGTGTCTCTGCAGGCACTCAGGAAGCTGTTCTACCTTGGAACTCCATGCAAC
Ensembl | human accession no.
NCBI accession no.
shipped in
ambient
storage temp.
−20°C
Quality Level
General description
MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
Legal Information
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Ridhima Gomkale et al.
Current biology : CB, 30(6), 1119-1127 (2020-03-07)
In mitochondria, the carrier translocase (TIM22 complex) facilitates membrane insertion of multi-spanning proteins with internal targeting signals into the inner membrane [1-3]. Tom70, a subunit of TOM complex, represents the major receptor for these precursors [2, 4-6]. After transport across
Sylvie Callegari et al.
FEBS letters, 590(23), 4147-4158 (2016-10-28)
Hydrophobic inner mitochondrial membrane proteins with internal targeting signals, such as the metabolite carriers, use the carrier translocase (TIM22 complex) for transport into the inner membrane. Defects in this transport pathway have been associated with neurodegenerative disorders. While the TIM22
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