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Merck
CN

EMU009421

MISSION® esiRNA

targeting mouse Wrn

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NACRES:
NA.51
UNSPSC Code:
41105324

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产品名称

MISSION® esiRNA, targeting mouse Wrn

description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

TTGGAAATGGAGATGCTGAAGTCTTTAGAAAACCTAAATAGTGACATGGTGGAACCCACTCACTCTAAATGGTTGGAAATGGGAACCAATGGGTGTCTTCCTCCTGAGGAGGAAGATGGACACGGAAATGAAGCCATCAAAGAGGAGCAGGAAGAAGAGGACCATTTATTGCCGGAACCCAACGCAAAGCAAATTAATTGCCTCAAGACCTATTTCGGACACAGCAGTTTTAAACCGGTTCAGTGGAAAGTCATCCATTCTGTATTAGAAGAGAGAAGAGATAATGTTGTTGTCATGGCAACTGGATATGGGAAGAGTCTGTGCTTCCAGTATCCGCCTGTTTATACAGGCAAGATTGGCATTGTCATTTCACCTCTCATTTCCTTAATGGAAGACCAAGTCCTCCAGCTTGAGCT

Ensembl | mouse accession no.

ENSMUSG00000031583

NCBI accession no.

NM_011721

shipped in

ambient

storage temp.

−20°C

Quality Level

100

Gene Information

mouse ... WRN(22427), Wrn(22427)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

存储类别

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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Venkateswarlu Popuri et al.
Nucleic acids research, 42(9), 5671-5688 (2014-03-14)
A variety of human tumors employ alternative and recombination-mediated lengthening for telomere maintenance (ALT). Human RecQ helicases, such as BLM and WRN, can efficiently unwind alternate/secondary structures during telomere replication and/or recombination. Here, we report a novel role for RECQL1

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