产品名称
MISSION® esiRNA, targeting mouse Cftr
description
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product line
MISSION®
form
lyophilized powder
esiRNA cDNA target sequence
GTCGTCTCGGCATTACAACCCTACATCTTCCTAGCAACGGTGCCAGGGCTAGTAGTCTTTATTTTACTGAGGGCCTACTTCCTTCATACAGCACAGCAGCTCAAACAACTGGAATCTGAAGGCAGGAGTCCAATTTTCACCCACCTTGTGACAAGCTTAAAAGGACTCTGGACACTTCGAGCCTTCCGACGCCAGACTTACTTTGAAACTCTGTTCCACAAAGCTCTGAATTTGCACACTGCCAACTGGTTTATGTATCTGGCAACCTTGCGCTGGTTCCAAATGAGAATAGACATGATATTTGTCCTCTTCTTCATTGTTGTTACCTTCATCTCCATTTTAACAACAGGTGAAGGAGAAGGAACAGCTGGTATTATTCTAACTTTAGCTATGAATATCATGAGTACTTTGCAGTGGGCTGTGA
Ensembl | mouse accession no.
NCBI accession no.
shipped in
ambient
storage temp.
−20°C
Quality Level
Gene Information
mouse ... CFTR(12638), Cftr(12638)
General description
MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
Legal Information
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Ye Chun Ruan et al.
Journal of cell science, 127(Pt 20), 4396-4408 (2014-08-12)
Mutations in CFTR lead to dysfunction of tubular organs, which is currently attributed to impairment of its conductive properties. We now show that CFTR regulates tight junction assembly and epithelial cell differentiation through modulation of the ZO-1-ZONAB pathway. CFTR colocalizes
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