description
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product line
MISSION®
form
lyophilized powder
esiRNA cDNA target sequence
CAATGTGATTGAACGCAACCCAGTGGACGTCAGTGCCATCCCTGAGCAGCGATGGAAACTGAAATGCATTTACTGCCGCAAGCGTATGAAGAGAGTGTCGGGTGCCTGCATCCAGTGCTCCTATGAGCACTGCTCCACATCCTTCCATGTGACCTGTGCGCATGCTGCTGGTGTCCTCATGGAACCCGATGACTGGCCCTATGTGGTGTCCATCACCTGCCTCAAGCACCGGGCCAGCGGAGCAGGGGGCCAGCTCCTGCGCACAGTGTCCCTGGGCCAGATCGTCATCACCAAGAACCGCAATGGGCTCTACTATCGCTGCCGGGTCATTGGCACCACTGCGCAGACATTCTACGAGGTCAACTTTGACGATGGCTCCTACAGTGACAACCTGTACCCAGAGAGCATCACGAGCAGAGACTGCCTA
Ensembl | mouse accession no.
NCBI accession no.
shipped in
ambient
storage temp.
−20°C
Quality Level
Gene Information
mouse ... JMJD2B(193796), Jmjd2b(193796)
General description
MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
Legal Information
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Amitabh Das et al.
Experimental cell research, 328(2), 361-378 (2014-09-07)
JMJD2A is a lysine trimethyl-specific histone demethylase that is highly expressed in a variety of tumours. The role of JMJD2A in tumour progression remains unclear. The objectives of this study were to identify JMJD2A-regulated genes and understand the function of
KDM4B promotes epithelial-mesenchymal transition through up-regulation of ZEB1 in pancreatic cancer.
Shuo Li et al.
Acta biochimica et biophysica Sinica, 47(12), 997-1004 (2015-10-30)
Lysine (K)-specific demethylase 4B (KDM4B) is a histone H3K9 demethylase and is reported to activate gene transcription through regulation of chromatin structures. Previous research has revealed that KDM4B plays special regulatory roles in colorectal, prostate and gastric cancers. However, its
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