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Merck
CN

EMU034911

MISSION® esiRNA

targeting mouse Abcb1a

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NACRES:
NA.51
UNSPSC Code:
41105324

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产品名称

MISSION® esiRNA, targeting mouse Abcb1a

description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

CAGCCCTGTTCTTGGACTGTCAGCTGGTATTTGGGCAAAGATATTGTCTTCATTTACTGATAAGGAACTCCATGCTTATGCAAAAGCTGGAGCAGTTGCTGAAGAAGTCTTAGCAGCCATCAGAACTGTGATTGCGTTTGGAGGACAAAAGAAGGAACTTGAAAGGTACAATAACAACTTGGAAGAAGCTAAAAGGCTGGGGATAAAGAAAGCTATCACGGCCAACATCTCCATGGGTGCAGCTTTTCTCCTTATCTATGCATCATATGCTCTGGCATTCTGGTATGGGACTTCCTTGGTCATCTCCAAAGAATACTCTATTGGACAAGTGCTCACTGTCTTCTTTTCCGTGTTAATTGGAGCATTCAGTGTTGGACAGGCATCTCCAAATATTGAAGCCTTCGCCAATGCACGAGGAGCAGCTTATGAAGTCTTCAAAATAATTGATAATAAGCCCAGTATAGACAGCTTCTCAAAGAGTGGGCAC

Ensembl | mouse accession no.

ENSMUSG00000040584

NCBI accession no.

NM_011076

shipped in

ambient

storage temp.

−20°C

Quality Level

100

Gene Information

mouse ... ABCB1A(18671), Abcb1a(18671)

相关类别

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

存储类别

12 - Non Combustible Liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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Nadejda Sigal et al.
Infection and immunity, 83(6), 2358-2368 (2015-04-01)
Human multidrug efflux transporters are known for their ability to extrude antibiotics and toxic compounds out of cells, yet accumulating data indicate they have additional functions in diverse physiological processes not related to drug efflux. Here, we show that the
Patric J Jansson et al.
The Journal of biological chemistry, 290(15), 9588-9603 (2015-02-28)
Multidrug resistance (MDR) is a major obstacle in cancer treatment. More than half of human cancers express multidrug-resistant P-glycoprotein (Pgp), which correlates with a poor prognosis. Intriguingly, through an unknown mechanism, some drugs have greater activity in drug-resistant tumor cells

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