产品名称
MISSION® esiRNA, targeting mouse Taz
form
lyophilized powder
description
Powered by Eupheria Biotech
product line
MISSION®
esiRNA cDNA target sequence
GCAGAACAGCTCCACAATCATTTCCAGCCTGGAAGATAGGCTTTGCCTGCCCAGTCTGTGCCCTGCAGTTCTTAGCCAAAGGAACACTGGGTCCTTCAGGATTTGGGAAGTGGTGGTACAGGAACCTGACCAAGCTTGCTTGGCTCTTTACTGCTTTTGAGATTCTTCCCTGTACAAAACTGAGGCTGGGAAATGGACTGATGCTTTTAATTCAGATAGATTGGCTCCCAATTCCTGCTGGATACCCTTTTTTATTCTTGAACATCTGACTCCTCTGGGTCTTGAGCTAAAAGAAGAGCCTTGGCTGTCCCTTATACTTGGTGGAGAAGGAAGGGACACTCTTAGGCAGGGGCCCCCTTCTCACCTCTCAGGGAGGGAACAGAGCAGGTAGTCAAGCAAATAGTTGGGTAGGAGAACAGGTTTCTTGGTCATAGGTACAGAAAGAAGACTCAATTGGTCCCTTGGATGGGCTACTACTTGCCCACTGCTCACA
Ensembl | mouse accession no.
NCBI accession no.
shipped in
ambient
storage temp.
−20°C
Quality Level
Gene Information
mouse ... TAZ(66826), Taz(66826)
General description
MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
Legal Information
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Libo Yan et al.
Archives of biochemistry and biophysics, 562, 31-36 (2014-08-01)
The Hippo-YAP pathway is altered and implicated as an oncogenic signaling pathway in many human cancers. Hypoxia is an important microenvironmental factor that promotes tumorigenesis. However, the effects of hypoxia on the two most important Hippo-YAP effectors, YAP (Yes-associated protein)
M Shanzer et al.
Oncogene, 34(32), 4190-4198 (2014-11-05)
The polyomavirus middle T antigen (PyMT) is an oncogene that activates the non-receptor tyrosine kinase, c-Src, and physically interacts with Taz (WWTR1). Taz is a pro-oncogenic transcription coactivator of the Tead transcription factors. The Hippo tumor suppressor pathway activates the
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