description
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product line
MISSION®
form
lyophilized powder
esiRNA cDNA target sequence
TCCCCAGAGACATGGAGAACGACAAGGCCATGCTGATAATGACCATGCTGTTGGCCAAAAAAGTGGCCAGTCACGCACCATCTTTGCTCCGTGATGTCTTCCACACGACTGTCAACTTTATTAACCAGAACCTATTCTCCTATGTGAGGAACTTGGTTAGAAACGAGATGGACTGAGGAGCCCGCACAAGCCCCGATGGTGACACTGCCTCCAGAGGAACCGCGACCATGGAAAGACCTTGGCCTGAAGACAGGTCCCAGAGAACAGCTGTCTCCCTATTTCCAGGTGGTGGGAACCCCAAGCTGGTGATTCACTGGACATCTCTGCGTTCAGCTTGAGTGTATCTGAAGAGTTTACGCCAGCTCCTGCATCCACACCATGTACCTTTGTCCTATCAGCTGTATGGGTTCCCACTTGGGAATGAAACTTAACAGCAGGCTGTAAGGCAGAAAAGCATCTTTGTAATGCCAAGTGACTGTTCCTGAGAGCCAGCTCTGGGCTGTCTTCACCATGTAGGTGGGCT
Ensembl | mouse accession no.
NCBI accession no.
shipped in
ambient
storage temp.
−20°C
Quality Level
Gene Information
mouse ... BID(12122), Bid(12122)
General description
MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
Legal Information
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Kohsuke Tsuchiya et al.
Nature communications, 10(1), 2091-2091 (2019-05-09)
Caspase-1 activated in inflammasomes triggers a programmed necrosis called pyroptosis, which is mediated by gasdermin D (GSDMD). However, GSDMD-deficient cells are still susceptible to caspase-1-mediated cell death. Therefore, here, we investigate the mechanism of caspase-1-initiated cell death in GSDMD-deficient cells.
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