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Merck
CN

EMU093231

MISSION® esiRNA

targeting mouse Akr1b7

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NACRES:
NA.51
UNSPSC Code:
41105324
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description

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Quality Level

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

CACCCTTATCTCACCCAGGAAAAACTGATCCAATACTGTCAATCCAAGGGCATCGCTGTTACAGCCTACAGTCCCCTGGGCTCCCCAGACAGGCCTTATGCCAAGCCAGAAGACCCCGTAGTAATGGAGATTCCCAAGATCAAAGAGATTGCTGCAAAACACAAGAAAACAGTAGCTCAGGTTCTGATTCGGTTCCATGTCCAAAGGAATGTGGTGGTGATCCCCAAGTCTGTGACACCCTCACGCATACAGGAGAACCTGCAGGTCTTCGACTTCCAGTTGAGTGAGGAGGACATGGCTGCCATTCTCAGCTTCAACAGGAACTGGAGGGCCTGTGACCTGTTGGATGCAAGGACTGAAGAGGACTATCCTTTCCACGAGGAATACTGAGGTCCACTTGCTTGATGAGATCCGTGCATGAT

Ensembl | mouse accession no.

NCBI accession no.

shipped in

ambient

storage temp.

−20°C

Gene Information

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

存储类别

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

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Xiaolong Du et al.
Experimental biology and medicine (Maywood, N.J.), 240(11), 1472-1479 (2015-05-15)
Angiogenesis is critical to wound repair due to its role in providing oxygen and nutrients that are required to support the growth and function of reparative cells in damaged tissues. Adenosine receptors are claimed to be of paramount importance in
Luofu Wang et al.
PloS one, 9(5), e96586-e96586 (2014-05-07)
The objective of this study was to investigate nanobubbles carrying androgen receptor (AR) siRNA and their in vitro and in vivo anti-tumor effects, when combined with ultrasonic irradiation, on androgen-independent prostate cancer (AIPC). Nanobubbles carrying AR siRNA were prepared using
Valerie N Barton et al.
Molecular cancer therapeutics, 14(3), 769-778 (2015-02-26)
Triple-negative breast cancer (TNBC) has the lowest 5-year survival rate of invasive breast carcinomas, and currently there are no approved targeted therapies for this aggressive form of the disease. The androgen receptor (AR) is expressed in up to one third
Fan Sun et al.
Journal of cellular physiology, 230(11), 2640-2646 (2015-02-03)
Adrenoreceptors (ARs) are widely expressed and play essential roles throughout the body. Different subtype adrenoceptors elicit distinct effects on cell proliferation, but knowledge remains scarce about the subtype-specific effects of β2-ARs on the proliferation of embryonic pluripotent stem (PS) cells
Xianwei Li et al.
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology, 19(5), 401-411 (2015-09-04)
Aldose reductase (AR) is known to play a crucial role in the mediation of diabetic and cardiovascular complications. Recently, several studies have demonstrated that allergen-induced airway remodeling and ovalbumin-induced asthma is mediated by AR. Epalrestat is an aldose reductase inhibitor

全球贸易项目编号

货号GTIN
EMU093231-20UG04061828531608
EMU093231-50UG04061828869435

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