description
Powered by Eupheria Biotech
product line
MISSION®
form
lyophilized powder
esiRNA cDNA target sequence
CACTGCTGTGCCTTATTGGAGAATCTTTCGATGACTACAGTGATGATGTGTGTGGAGCTGTTGTTAATGTTAGAGCTAAAGGCGATAAGATAGCAATATGGACTACTGAGAGTGAAAACAGAGATGCAGTCACACACATAGGGAGGGTATACAAGGAAAGGTTAGGACTTCCTCCGAAGATAGTGATTGGTTATCAGTCCCACGCAGACACAGCTACAAAGAGCGGCTCCACCACTAAAAATAGGTTTGTTGTTTAAAAAGACACCTTCTGAGTATTCTCACAGGAGACTGCGTCACGCAATCGAGATTGGGAGCTGAACCAAAGCCTCATCAAAGCAGAGTGGACTGCACTGAAGTTGATTCCATCCAAGTGTTGCTAAGATATAAGAGAAGTCTCATTCGCCTTTGTCTTGTACTTCTGTGTTCATTCTCCTCCCC
Ensembl | mouse accession no.
NCBI accession no.
shipped in
ambient
storage temp.
−20°C
Quality Level
Gene Information
mouse ... EIF4E(13684), Eif4e(13684)
General description
MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
Legal Information
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
miR-141 confers docetaxel chemoresistance of breast cancer cells via regulation of EIF4E expression.
Ya-Sai Yao et al.
Oncology reports, 33(5), 2504-2512 (2015-03-31)
Resistance to docetaxel, a chemotherapy drug for breast cancer (BC) treatment, occurs in ~50% of patients, and the underlying molecular mechanisms of drug resistance are not fully understood. Gene regulation through miR-141 has been proven to play an important role
Monique E Beaudoin et al.
Nucleic acids research, 36(21), 6835-6847 (2008-10-28)
Expression of amyloid precursor protein (APP) is critical to the etiology of Alzheimer's disease (AD). Consequently, regulating APP expression is one approach to block disease progression. To this end, APP can be targeted at the levels of transcription, translation, and
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