描述
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质量水平
产品线
MISSION®
表单
lyophilized powder
esiRNA cDNA靶序列
CACTGCTGTGCCTTATTGGAGAATCTTTCGATGACTACAGTGATGATGTGTGTGGAGCTGTTGTTAATGTTAGAGCTAAAGGCGATAAGATAGCAATATGGACTACTGAGAGTGAAAACAGAGATGCAGTCACACACATAGGGAGGGTATACAAGGAAAGGTTAGGACTTCCTCCGAAGATAGTGATTGGTTATCAGTCCCACGCAGACACAGCTACAAAGAGCGGCTCCACCACTAAAAATAGGTTTGTTGTTTAAAAAGACACCTTCTGAGTATTCTCACAGGAGACTGCGTCACGCAATCGAGATTGGGAGCTGAACCAAAGCCTCATCAAAGCAGAGTGGACTGCACTGAAGTTGATTCCATCCAAGTGTTGCTAAGATATAAGAGAAGTCTCATTCGCCTTTGTCTTGTACTTCTGTGTTCATTCTCCTCCCC
基因组数据库 |小鼠登记号
NCBI登记号
运输
ambient
储存温度
−20°C
基因信息
mouse ... EIF4E(13684), Eif4e(13684)
一般描述
MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
法律信息
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
10 - Combustible liquids
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
miR-141 confers docetaxel chemoresistance of breast cancer cells via regulation of EIF4E expression.
Ya-Sai Yao et al.
Oncology reports, 33(5), 2504-2512 (2015-03-31)
Resistance to docetaxel, a chemotherapy drug for breast cancer (BC) treatment, occurs in ~50% of patients, and the underlying molecular mechanisms of drug resistance are not fully understood. Gene regulation through miR-141 has been proven to play an important role
Monique E Beaudoin et al.
Nucleic acids research, 36(21), 6835-6847 (2008-10-28)
Expression of amyloid precursor protein (APP) is critical to the etiology of Alzheimer's disease (AD). Consequently, regulating APP expression is one approach to block disease progression. To this end, APP can be targeted at the levels of transcription, translation, and
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