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Merck
CN

EMU154511

MISSION® esiRNA

targeting mouse Erbb3

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NACRES:
NA.51
UNSPSC Code:
41105324

主要文件

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产品名称

MISSION® esiRNA, targeting mouse Erbb3

description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

CCCCGTGAAGTCAAGAATTTCCACCTTTTCTCAAACAAAAAACCATTTCTTTGACACATTTGAATTAATAGCAGGACTTGCCCTTTGGGCCCATTCTTAGGTAAGATGAGGGTCTTTGAGCACAAGTACTATGAGATCTGTCAGTCAATCTAATAACCAGGCAGGTAATTAAGTGGCTCAAGAGCAAATAGGTTATTCAGTGCGGGTGTACCAGGCAGAGATGATTCATCTACCAAGTGGAACAGGAGAGGCCGGCTGTGATTTCATCGTGCTATTCAGAATGGGTACTATGTAAACTGTAAGGATTATTTATTTCAGGAACTTGTCACTCAGCATGTTTCAGATGACAGTTGACCACAGGTTACTAAAACTGTGGACAGCAAAACCTCAGAAAATGGGGAATTGAGCCTTGAAGAAGCAAAGCCACAGGTCCAGGATTCAAAATCCTCCCAATTCCCATGCCTGTGATTTAACTATAAAGTGTATGTGTGTGTGTGTAAAGCCGGGCCT

Ensembl | mouse accession no.

ENSMUSG00000018166

NCBI accession no.

NM_010153

shipped in

ambient

storage temp.

−20°C

Quality Level

100

Gene Information

mouse ... ERBB3(13867), Erbb3(13867)

相关类别

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

存储类别

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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C He et al.
Oncogene, 34(50), 6040-6054 (2015-03-24)
Mechanisms underlying ovarian cancer initiation and progression are unclear. Herein, we report that the Yes-associated protein (YAP), a major effector of the Hippo tumor suppressor pathway, interacts with ERBB signaling pathways to regulate the initiation and progression of ovarian cancer.
Maicol Mancini et al.
Science signaling, 8(379), ra53-ra53 (2015-06-04)
Despite initial responses to targeted kinase inhibitors, lung cancer patients presenting with primary epidermal growth factor receptor (EGFR) mutations acquire resistance, often due to a second-site mutation (T790M). However, clinical trials found no survival benefits in patients treated with a

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