description
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product line
MISSION®
form
lyophilized powder
esiRNA cDNA target sequence
GCGGTCTCTTCTCTCTCTCCTTCCTTTTGTGAGATTTTTTTGATCTTCAGCTACATTTTCAGCTTTGTGAGAAACCTCATCATCAAAGGAGATGGCTAGCAATGTTACCAACAAGACAGATCCTCGGTCCATGAATTCCCGTGTATTCATTGGGAATCTCAACACTCTGGTGGTCAAGAAGTCTGATGTGGAGGCCATCTTTTCAAAGTATGGCAAAATTGTGGGCTGCTCTGTGCATAAAGGCTTTGCCTTTGTCCAGTATGTTAATGAAAGAAATGCCCGAGCTGCTGTAGCTGGCGAGGATGGCAGAATGATTGCTGGCCAGGTTTTAGATATTAACCTGGCTGCAGAGCCAAAAGTGAACCGAGGAAAAGCAGGTGTGAAACGATCTGCAGCGGAGATGTACGGGTCAGTACCAGAACACCCTTCTCCGTCCCCTCTACTCAGTTCCTCATTTGACTTGGACTATGACTTTCAACGGGATTATTATGACAGGATGTACAGTTACCCAGCG
Ensembl | mouse accession no.
NCBI accession no.
shipped in
ambient
storage temp.
−20°C
Quality Level
Gene Information
mouse ... HNRNPC(15381), Hnrnpc(15381)
General description
MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
Legal Information
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Zuzana Cieniková et al.
RNA (New York, N.Y.), 21(11), 1931-1942 (2015-09-16)
The human hnRNP C is a ubiquitous cellular protein involved in mRNA maturation. Recently, we have shown that this protein specifically recognizes uridine (U) pentamers through its single RNA recognition motif (RRM). However, a large fraction of natural RNA targets
Na Li et al.
Nature cell biology, 16(11), 1080-1091 (2014-10-27)
Cyclin C was cloned as a growth-promoting G1 cyclin, and was also shown to regulate gene transcription. Here we report that in vivo cyclin C acts as a haploinsufficient tumour suppressor, by controlling Notch1 oncogene levels. Cyclin C activates an
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