F0429
氟尼辛葡甲胺
≥98% (HPLC)
别名:
2-[[2-甲基-3-（三氟甲基）苯基]氨基] -3-吡啶羧酸葡甲胺盐, 氟尼辛甲葡胺
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关于此项目
经验公式（希尔记法）:
C14H11F3N2O2·C7H17NO5
化学文摘社编号:
分子量:
491.46
EC 号:
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
质量水平
方案
≥98% (HPLC)
表单
powder
颜色
white to beige
mp
136.6-137.4 °C
溶解性
H2O: freely soluble
储存温度
room temp
SMILES字符串
CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.Cc1c(Nc2ncccc2C(O)=O)cccc1C(F)(F)F
InChI
1S/C14H11F3N2O2.C7H17NO5/c1-8-10(14(15,16)17)5-2-6-11(8)19-12-9(13(20)21)4-3-7-18-12;1-8-2-4(10)6(12)7(13)5(11)3-9/h2-7H,1H3,(H,18,19)(H,20,21);4-13H,2-3H2,1H3/t;4-,5+,6+,7+/m.0/s1
InChI key
MGCCHNLNRBULBU-WZTVWXICSA-N
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相关类别
应用
氟尼辛葡甲胺已被用作电喷雾电离质谱（LC-ESI/MS）检测中的非固醇类消炎药物标准品。
氟尼辛葡甲胺（IC50 = 1 nM）可用作动物药物，用于治疗马的肠缺血、绞痛和内毒素血症。
生化/生理作用
COX1、COX2 和 PLA2 抑制剂非麻醉性镇痛、解热、抗炎。
氟尼辛葡甲胺是一种非固醇类消炎药，可阻止前列腺素合成。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
J Cuervo-Arango et al.
Theriogenology, 77(3), 514-524 (2011-10-01)
The development of hemorrhagic anovulatory follicles (HAF) involves luteinization and hemorrhage of the follicle. This is observed on ultrasound as an increase in the echogenicity of the granulosa layer and formation of echoic particles in the antrum. The inhibition of
A Review on Flunixin Meglumine
Faiza H, et al.
International journal of medicine and medical research, 1(2), 136-138 (2016)
A J Morton et al.
Equine veterinary journal. Supplement, (39)(39), 112-116 (2011-08-04)
The effects of prostaglandins and nonsteroidal anti-inflammatory drugs (NSAIDs) on repair of equine intestinal mucosa are important since most horses with gastrointestinal diseases are routinely treated with NSAIDs, such as flunixin meglumine (FM), and these drugs can be toxic to
Kara L Schulz et al.
American journal of veterinary research, 72(11), 1431-1438 (2011-10-26)
To characterize amphotericin B-induced lameness in cattle and to ascertain the analgesic effects of flunixin meglumine by use of multimodal assessment. 10 healthy Holstein steers free from musculoskeletal disease. Steers were randomly allocated to a treatment or negative control group.
Cynthia L Deyrup et al.
Journal of the American Veterinary Medical Association, 241(2), 249-253 (2012-07-07)
To determine whether cull dairy cows with signs of certain clinical conditions, termed suspect, are more likely than healthy-appearing cull dairy cows to have violative concentrations of flunixin meglumine in their tissues at slaughter. Cross-sectional study. 961 cull dairy cows.
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