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Merck
CN

F1058

FSL-Fluorescein

别名:

FSL-FLRO4(fluorescein)-SA2-L1

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关于此项目

经验公式(希尔记法):
C73H109N4O15PS
分子量:
1345.70
UNSPSC Code:
41116100
PubChem Substance ID:
NACRES:
NA.32
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Quality Level

storage temp.

−20°C

SMILES string

CCCCCCCC\C=C/CCCCCCCC(=O)OCC(COP(O)(=O)OCCNC(=O)CCCCC(=O)NCCCCCNC(=S)Nc1ccc2c(c1)C(=O)OC23c4ccc(O)cc4Oc5cc(O)ccc35)OC(=O)CCCCCCC\C=C/CCCCCCCC

InChI

1S/C73H109N4O15PS/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-32-40-69(82)87-55-60(90-70(83)41-33-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)56-89-93(85,86)88-51-50-75-68(81)39-35-34-38-67(80)74-48-36-31-37-49-76-72(94)77-57-42-45-62-61(52-57)71(84)92-73(62)63-46-43-58(78)53-65(63)91-66-54-59(79)44-47-64(66)73/h17-20,42-47,52-54,60,78-79H,3-16,21-41,48-51,55-56H2,1-2H3,(H,74,80)(H,75,81)(H,85,86)(H2,76,77,94)/b19-17-,20-18-

InChI key

OZXSVOLFZKVFHP-CLFAGFIQSA-N

Application

All FSL constructs disperse in biocompatible media and spontaneously and stably incorporate into cell membranes. Cells modified with FSL constructs are known as kodecytes and usually maintain their normal vitality and functionality. FSL-fluorescein has been specifically designed to create fluorescein-labeled live cells (kodecytes) but can also be used to modify other hydrophobic surfaces including fixed cells, virions, and solid phase surfaces. Fluorescein-labeled kodecytes can be visualized at the approximate absorbance wavelength of 488 nm and emission at 518 nm.
All FSL constructs disperse in biocompatible media and spontaneously and stably incorporate into cell membranes. FSL-fluorescein has been specifically designed to create fluorescein-labeled live cells (kodecytes) but can also be used to modify other hydrophobic surfaces including fixed cells, virions, and solid phase surfaces.

Other Notes

FSL-fluorescein is a KODE technology construct designed to label hydrophobic surfaces including living cells with biotin. All FSL constructs consist of three essential designable features:
  • functional component (F)
  • spacer (S)
  • diacyl lipid (L)
FSL-fluorescein is comprised of a fluorescein residue representing F, conjugated via a spacer (SA2) to an an activated adipate derivative of dioleoylphosphatidylethanolamine (L1).
Packaged as 1 mg FSL-Fluorescein with 0.42 mg sodium bicarbonate to improve solubility.

Legal Information

KODE Constructs are supplied by KODE Biotech Materials Limited under license from KODE Biotech Limited.
KODE is a trademark of KODE Biotech Ltd.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Victor Naumenko et al.
Molecular therapy oncolytics, 10, 14-27 (2018-08-04)
Oncolytic virus (OV) therapy is an emerging cancer treatment that uses replicating viruses to infect and kill tumor cells and incite anticancer immunity. While the approach shows promise, it currently fails most patients, indicating strategies to improve OV activity are

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Instructions

全球贸易项目编号

货号GTIN
F1058-1MG04061826703236

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