F112
(+)-芬氟拉明 盐酸盐
serotonin uptake inhibitor, powder
别名:
(+)-N-Ethyl-α-methyl-m-[trifluoromethyl]phenethylamine hydrochloride, Dexfenfluramine hydrochloride
产品名称
(+)-芬氟拉明 盐酸盐,
表单
powder
质量水平
药品控制
USDEA Schedule IV
颜色
white to off-white
溶解性
H2O: soluble 10 mg/mL
应用
forensics and toxicology
储存温度
room temp
SMILES字符串
Cl[H].CCN[C@@H](C)Cc1cccc(c1)C(F)(F)F
InChI
1S/C12H16F3N.ClH/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15;/h4-6,8-9,16H,3,7H2,1-2H3;1H/t9-;/m0./s1
InChI key
ZXKXJHAOUFHNAS-FVGYRXGTSA-N
生化/生理作用
(+)-Fenfluramine is a serotonin uptake inhibitor; anoxexic.
(+)-Fenfluramine is a serotonin uptake inhibitor; anoxexic. (+)-Fenfluramine is neurotoxic on prolonged administration or at high dosage. (+)-Fenfluramine releases serotonin from axon terminals by a nonexocytotic mechanism.
其他说明
Active isomer
警示用语：
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
个人防护装备
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
法规信息
新产品
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Rimonabant redux and strategies to improve the future outlook of CB1 receptor neutral-antagonist/inverse-agonist therapies.
Sara Jane Ward et al.
Obesity (Silver Spring, Md.), 19(7), 1325-1334 (2011-04-09)
L Rochette et al.
Annales de cardiologie et d'angeiologie, 57(3), 136-138 (2008-06-27)
A novel concept of "gasotransmitter" arrived recently. They are small molecules of endogenous gases. Hydrogene sulfide (H2S) is qualified as the third gasotransmitter beside nitric oxide (NO) and carbon monoxide (CO). The physiological functions of endogenous H2S are not well-known.
Richard W Foltin
Physiology & behavior, 103(5), 493-500 (2011-04-23)
We examined the effects of periodic access to a palatable, high sugar content food (candy) in 8 male baboons on the anorectic response to d-amphetamine, which increases dopamine, and dexfenfluramine, which increases serotonin. During candy access, up to 200 candies
Effects of d- and 1-fenfluramine on striatal homovanillic acid concentrations in rats after pharmacological manipulation of brain serotonin.
V Crunelli et al.
Pharmacological research communications, 12(3), 215-223 (1980-03-01)
Korneel Rabaey et al.
Current opinion in biotechnology, 22(3), 371-377 (2011-03-01)
The production of biofuels and biochemicals is highly electron intensive. To divert fermentative and respiratory pathways to the product of interest, additional electrons (i.e. reducing power) are often needed. Meanwhile, the past decade has seen the breakthrough of sustainable electricity
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