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Merck
CN

F1141

Bovine Fibronectin

from bovine plasma, liquid, suitable for cell culture

别名:

纤连蛋白 溶液 来源于人类成纤维细胞

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关于此项目

UNSPSC Code:
12352202
eCl@ss:
42020141
NACRES:
NA.75
EC Number:
289-149-2
MDL number:
Biological source:
bovine plasma
Form:
solution
Technique(s):
cell culture | mammalian: suitable
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产品名称

纤连蛋白牛血浆, solution, sterile-filtered, BioReagent, suitable for cell culture

biological source

bovine plasma

Quality Level

sterility

sterile-filtered

product line

BioReagent

form

solution

packaging

pkg of 1 mg, pkg of 2 mg, pkg of 5 mg

technique(s)

cell culture | mammalian: suitable

surface coverage

1‑5 μg/cm2

UniProt accession no.

binding specificity

Peptide Source: Collagen
, Peptide Source: Fibrinogen

shipped in

wet ice

storage temp.

2-8°C

Gene Information

bovine ... FN1(280794)

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General description

纤连蛋白是一种普遍存在的细胞外基质蛋白。它是一种镶嵌蛋白,由三种的重复模块共有氨基酸序列组成。纤连蛋白属于一类高分子量糖蛋白。细胞纤连蛋白由成纤维细胞表达,血浆纤连蛋白通常由肝细胞释放。

Application

纤连蛋白(FN)牛血浆可用于:
  • 纤连蛋白和吸附分析(ELISA(酶联免疫吸附测定))
  • 跨孔迁移
  • 纤连蛋白测定

Biochem/physiol Actions

纤连蛋白参与细胞粘附、细胞骨架组织、致癌性转化、细胞迁移、吞噬、止血和胚胎分化。

Analysis Note

采用免疫电泳法评估蛋白质的均一性。

Other Notes

产品F1141,牛血浆纤连蛋白是pH 7.5的0.05 M TBS溶液。

pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

存储类别

12 - Non Combustible Liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves

法规信息

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CCL2/CCR2 chemokine signaling coordinates survival and motility of breast cancer cells through Smad3 and p42/44MAPK dependent mechanisms
Fang W B, et al.
The Journal of biological chemistry, jbc-M112 (2012)
FIBRONECTIN AUTOANTIBODIES
Autoantibodies, 221-251 (2007)
Tests to predict preeclampsia
Chesley's Hypertensive Disorders in Pregnancy, 221-251 (2015)
Enhanced fibronectin adsorption on carbon nanotube/poly (carbonate) urethane: independent role of surface nano-roughness and associated surface energy
Khang D, et al.
Biomaterials, 28(32), 4756-4768 (2007)
Role of subnano-, nano-and submicron-surface features on osteoblast differentiation of bone marrow mesenchymal stem cells
Khang D, et al.
Biomaterials, 33(26), 5997-6007 (2012)

商品

The extracellular matrix (ECM) and its attachment factor components are discussed in this article in relation to their function in structural biology and their availability for in vitro applications.

3D cell culture overview. Learn about 2D vs 3D cell culture, advantages of 3D cell culture, and techniques available to develop 3D cell models

The extracellular matrix (ECM) is secreted by cells and surrounds them in tissues.

Fibronectin (FN) plays crucial roles in extracellular matrix fibril assembly and cellular interactions.

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实验方案

Dilute fibronectin for cell attachment, varying per cell type. Coating protocol, products, and FAQs provided.

全球贸易项目编号

货号GTIN
F1141-1MG04061835568444
F1141-2MG04061833611678
F1141-5MG04061835514144

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