F1293
非那雄胺
≥98% (HPLC), Selective 5α-reductase inhibitor, powder
别名:
N-叔丁基-3-氧代-4-氮杂-5α-雄甾-1-烯-17β-甲酰胺, MK-906, N-(2-甲基-2-丙基)-3-氧代-4-氮杂-5α-雄甾-1-烯-17β-甲酰胺
选择规格
关于此项目
产品名称
非那雄胺, ≥98% (HPLC), powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: soluble >20 mg/mL
storage temp.
room temp
SMILES string
[H][C@@]12CC[C@@]3([H])[C@]4([H])CC[C@H](C(=O)NC(C)(C)C)[C@@]4(C)CC[C@]3([H])[C@@]1(C)C=CC(=O)N2
InChI
1S/C23H36N2O2/c1-21(2,3)25-20(27)17-8-7-15-14-6-9-18-23(5,13-11-19(26)24-18)16(14)10-12-22(15,17)4/h11,13-18H,6-10,12H2,1-5H3,(H,24,26)(H,25,27)/t14-,15-,16-,17+,18+,22-,23+/m0/s1
InChI key
DBEPLOCGEIEOCV-WSBQPABSSA-N
Gene Information
human ... HSD3B1(3283), SRD5A1(6715), SRD5A2(6716)
rat ... Hsd3b1(360348), Srd5a1(24950), Srd5a2(64677)
Application
- as a component of L-15 media to investigate the effects of finasteride exposure on brain, liver and testis tissues
- in culture medium to treat tumor cells in vitro
- as a positive control to treat benign prostatic hyperplasia (BPH)
- to examine its effect on structural and molecular biology on the ventral prostate of senile mice
Biochem/physiol Actions
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Repr. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves