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Merck
CN

F131

FPL 64176

≥98% (HPLC), powder

别名:

2,5-Dimethyl-4-[2-(phenylmethyl)benzoyl]-1H-pyrrole-3-carboxlic acid methyl ester

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关于此项目

经验公式(希尔记法):
C22H21NO3
化学文摘社编号:
分子量:
347.41
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
Storage condition:
desiccated, protect from light
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Quality Level

assay

≥98% (HPLC)

form

powder

storage condition

desiccated, protect from light

color

white to beige

solubility

DMSO: >20 mg/mL (Solutions should be freshly prepared.), H2O: insoluble

storage temp.

2-8°C

SMILES string

COC(=O)c1c(C)[nH]c(C)c1C(=O)c2ccccc2Cc3ccccc3

InChI

1S/C22H21NO3/c1-14-19(20(15(2)23-14)22(25)26-3)21(24)18-12-8-7-11-17(18)13-16-9-5-4-6-10-16/h4-12,23H,13H2,1-3H3

InChI key

MDMWHKZANMNXTF-UHFFFAOYSA-N

Gene Information

rat ... Cacnb3(25297)

Biochem/physiol Actions

Potent Ca2+ channel (L-type) activator.

Legal Information

Manufactured and sold with permission from Astra Charnwood.

Disclaimer

Photosensitive

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Jeffrey J Ross et al.
The Journal of clinical investigation, 116(12), 3139-3149 (2006-11-14)
Smooth muscle formation and function are critical in development and postnatal life. Hence, studies aimed at better understanding SMC differentiation are of great importance. Here, we report that multipotent adult progenitor cells (MAPCs) isolated from rat, murine, porcine, and human
R J Large et al.
American journal of physiology. Cell physiology, 299(5), C1180-C1194 (2010-08-20)
Hyaluronan, a joint lubricant and regulator of synovial fluid content, is secreted by fibroblast-like synoviocytes lining the joint cavity, and secretion is greatly stimulated by Ca(2+)-dependent protein kinase C. This study aimed to define synoviocyte membrane currents and channels that
Louise Adermark et al.
The European journal of neuroscience, 29(1), 32-41 (2009-01-06)
Long-term depression (LTD) at striatal synapses is mediated by postsynaptic endocannabinoid (eCB) release and presynaptic cannabinoid 1 receptor (CB(1)R) activation. Previous studies have indicated that eCB mobilization at excitatory synapses might be regulated by afferent activation. To further address the
Zhong Zhang et al.
American journal of physiology. Renal physiology, 299(4), F862-F871 (2010-07-16)
Multiple voltage-gated Ca(2+) channel (Ca(V)) subtypes have been reported to participate in control of the juxtamedullary glomerular arterioles of the kidney. Using the patch-clamp technique, we examined whole cell Ca(V) currents of pericytes that contract descending vasa recta (DVR). The
Y Zhang et al.
Acta physiologica (Oxford, England), 198(2), 143-158 (2009-11-06)
To investigate the effect of increases in extracellular Ca(2+) entry produced by the L-type Ca(2+) channel agonist FPL-64176 (FPL) upon acute atrial arrhythmogenesis in intact Langendorff-perfused mouse hearts and its dependence upon diastolic Ca(2+) release from sarcoplasmic reticular Ca(2+) stores.

全球贸易项目编号

货号GTIN
F131-25MG04061832961613
F131-100MG04061832961606

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