F132
氟西汀 盐酸盐
≥98% (TLC), solid, selective serotonin reuptake inhibitor
别名:
氟西汀 HCl, (±)-N-甲基-γ-[4-(三氟甲基)苯氧基]苯丙胺 盐酸盐, LY-110,140 盐酸盐, Prozac®
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关于此项目
经验公式（希尔记法）:
C17H18F3NO · HCl
化学文摘社编号:
分子量:
345.79
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
260-101-2
MDL number:
产品名称
氟西汀 盐酸盐, solid
InChI key
GIYXAJPCNFJEHY-UHFFFAOYSA-N
InChI
1S/C17H18F3NO.ClH/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20;/h2-10,16,21H,11-12H2,1H3;1H
SMILES string
CNCCC(C1=CC=CC=C1)OC2=CC=C(C(F)(F)F)C=C2.[H]Cl
form
solid
color
white
solubility
H2O: 4 mg/mL
DMSO: >5 mg/mL
originator
Eli Lilly
Quality Level
Gene Information
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General description
盐酸氟西汀是一种精神类药物，是最早的抗抑郁药物之一，是选择性血清素再摄取抑制剂。它是百忧解有效成分之一。®
Legal Information
经 Eli Lilly and Company 授权销售。
Prozac is a registered trademark of Eli Lilly and Co.
Application
盐酸氟西汀可以用于研究它对于小鼠放射药物 123I-标记2-（（2-（（二甲基氨基）甲基）苯基）硫基）-5-碘苯基胺([123I]ADAM)和SERT（血清素载体）结合的作用。它也被用于长期治疗缺乏光线的动物。它还被用作血清素再摄取抑制剂，以研究其对鱼类急性应激的影响。
Biochem/physiol Actions
盐酸氟西汀作用于突触前末梢，它能够避免血清素再摄取，导致突触细胞外液体中血清素积累。
选择性羟色胺再摄取抑制剂；抗抑郁剂。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - STOT RE 2 - STOT SE 3
target_organs
Central nervous system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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