氰戊菊酯

Name: 氰戊菊酯
Brand: SIGMA

≥97%

别名:

α-氰基-3-苯氧基苄基-α-(4-氯苯基)-3-甲基丁酸酯

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关于此项目

经验公式（希尔记法）:

C₂₅H₂₂ClNO₃

化学文摘社编号:

51630-58-1

分子量:

419.90

UNSPSC Code:

12352200

NACRES:

NA.77

PubChem Substance ID:

329799681

MDL number:

MFCD00055324

Beilstein/REAXYS Number:

2025982

Assay:

≥97%

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属性

Quality Segment

200

assay

≥97%

storage temp.

−20°C

SMILES string

CC(C)C(C(=O)OC(C#N)c1cccc(Oc2ccccc2)c1)c3ccc(Cl)cc3

InChI

1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3

InChI key

NYPJDWWKZLNGGM-UHFFFAOYSA-N

说明

General description

Fenvalerate an ester molecule, exists in four stereoisomers with two chiral centers.

Application

Fenvalerate has been used to study the effect of Fen exposure on reproductive functions.

Biochem/physiol Actions

Fenvalerate has good insecticidal potential and is less toxic to animals. It might cause endocrine disruption and reproductive dysfunction in humans. Metabolism of fenvalerate includes oxidation, ester cleavage and conjugation reaction. It is stable at pH 5 and 7, while it gets hydrolyzed at pH 9. In rat models it is found to hinder the action of mitochondrial enzymes.

II 型拟除虫菊酯。强效钙调磷酸酶（蛋白磷酸酶 2B）抑制剂。

Fenvalerate is a type II semi-synthetic pyrethrin, which acts as a potent inhibitor of calcineurin (protein phosphatase 2B). This inhibitory action results in cellular hyperexcitability by causing non-mutated calcium channels to remain open for an extended period of time allowing an abundance of Ca2+ to enter the cell.