F3385
胎球蛋白 from fetal bovine serum
lyophilized powder, BioReagent, suitable for cell culture
别名:
胎球蛋白 from fetal bovine serum, 胎球蛋白 来源于胎牛血清
产品线
BioReagent
质量水平
表单
lyophilized powder
分子量
48.4 kDa
技术
cell culture | mammalian: suitable
杂质
≤0.3% free N-acetylneuraminic acid
溶解性
H2O: 1 mg/mL
储存温度
2-8°C
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一般描述
来自胎牛血清的胎球蛋白是一种血浆糖蛋白。它是一种64 kDa的糖蛋白,由肝脏和脂肪组织产生。
在胚胎癌细胞培养中,以500 mg/ml的浓度,将来自胎牛血清并用作胎球蛋白的一种糖蛋白(与胰岛素、转铁蛋白和2-巯基乙醇一同)添加到无血清的F12培养基中。
在胚胎癌细胞培养中,以500 mg/ml的浓度,将来自胎牛血清并用作胎球蛋白的一种糖蛋白(与胰岛素、转铁蛋白和2-巯基乙醇一同)添加到无血清的F12培养基中。
应用
胎牛血清中的胎球蛋白已用于:
- 作为测定神经氨酸酶活性的底物
- 验证唾液酸酶的特异性
- 稳定m-钙蛋白酶
生化/生理作用
胎球蛋白可作为胰岛素受体酪氨酸激酶的抑制剂。它可调节骨骼重塑和钙的代谢。胎球蛋白可调节血管钙化、胰岛素抵抗、蛋白酶活性控制、角质形成细胞迁移和乳腺肿瘤细胞增殖信号。它可作为神经退行性疾病的一种生物标志物。胎球蛋白具有抗炎症属性。
制备说明
Prepared by ammonium sulfate fractionation of fetal bovine serum by the method of Pederson, K.O., J. Phys. and Colloid Chem., 51, 164 (1947).
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
监管及禁止进口产品
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