F3385
胎球蛋白 from fetal bovine serum
lyophilized powder, BioReagent, suitable for cell culture
别名:
胎球蛋白 from fetal bovine serum, 胎球蛋白 来源于胎牛血清
product line
BioReagent
form
lyophilized powder
mol wt
48.4 kDa
technique(s)
cell culture | mammalian: suitable
impurities
≤0.3% free N-acetylneuraminic acid
solubility
H2O: 1 mg/mL
storage temp.
2-8°C
Quality Level
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General description
来自胎牛血清的胎球蛋白是一种血浆糖蛋白。它是一种64 kDa的糖蛋白，由肝脏和脂肪组织产生。
在胚胎癌细胞培养中，以500 mg/ml的浓度，将来自胎牛血清并用作胎球蛋白的一种糖蛋白（与胰岛素、转铁蛋白和2-巯基乙醇一同）添加到无血清的F12培养基中。
在胚胎癌细胞培养中，以500 mg/ml的浓度，将来自胎牛血清并用作胎球蛋白的一种糖蛋白（与胰岛素、转铁蛋白和2-巯基乙醇一同）添加到无血清的F12培养基中。
Application
胎牛血清中的胎球蛋白已用于：
- 作为测定神经氨酸酶活性的底物
- 验证唾液酸酶的特异性
- 稳定m-钙蛋白酶
Biochem/physiol Actions
胎球蛋白可作为胰岛素受体酪氨酸激酶的抑制剂。它可调节骨骼重塑和钙的代谢。胎球蛋白可调节血管钙化、胰岛素抵抗、蛋白酶活性控制、角质形成细胞迁移和乳腺肿瘤细胞增殖信号。它可作为神经退行性疾病的一种生物标志物。胎球蛋白具有抗炎症属性。
Preparation Note
Prepared by ammonium sulfate fractionation of fetal bovine serum by the method of Pederson, K.O., J. Phys. and Colloid Chem., 51, 164 (1947).
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
监管及禁止进口产品
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