产品名称
抗 成纤维细胞生长因子-碱性 (1-24) 兔抗, fractionated antiserum, lyophilized powder
biological source
rabbit
conjugate
unconjugated
antibody form
fractionated antiserum
antibody product type
primary antibodies
clone
polyclonal
form
lyophilized powder
species reactivity
human, bovine, rat
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
indirect ELISA: suitable
western blot: 1:1,000
impurities
endotoxin, tested
UniProt accession no.
application(s)
research pathology
storage temp.
2-8°C
target post-translational modification
unmodified
Quality Level
Gene Information
bovine ... FGF2(281161)
human ... FGF2(2247)
rat ... Fgf2(54250)
Analysis Note
生物活性：抗成纤维细胞生长因子-碱性（1-24）导致FGF-碱性的促有丝分裂活性呈剂量依赖性降低，因此1:50的最终稀释度中和了1个单位FGF碱性的生物活性。
Application
兔源抗碱性成纤维细胞生长因子（1-24）抗体可用于：
- 免疫组化
- 免疫染色
- 免疫印迹
Biochem/physiol Actions
碱性成纤维细胞生长因子（也称为bFGF）是一种多效性细胞因子，是一种有效的促有丝分裂因子。bFGF与其同源受体酪氨酸激酶FGFR结合后，能够激活MAPK和PI3K等途径，并在多种细胞类型中产生细胞效应。据报道，碱性成纤维细胞生长因子可诱导成纤维细胞增殖，分化，伤口愈合和再生，肢体形成，组织重塑和血管生成。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
碱性成纤维细胞生长因子（FGFb），也称为NUDT6（nudix（核苷二磷酸连接部分X）型基序6）由定位于人染色体4q28.1的基因编码。FGFb基因跨越基因组DNA上的34271 bp，包含16个外显子和6个内含子。FGFb RNA转录物在各种人体组织中表达，包括肝脏，胸腺，脾脏，外周血白细胞，心脏骨骼肌，睾丸，结肠和肾脏。
Immunogen
对应于人牛FGF2（1-24）的合成肽序列
Physical form
从磷酸盐缓冲生理盐水中的0.2 μm滤过溶液冻干。
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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