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Merck
CN

F3422

Flt-3/Flk-2 ligand human

recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture, ≥98% (SDS-PAGE and HPLC)

别名:

FL

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关于此项目

UNSPSC Code:
51111800
NACRES:
NA.32
MDL number:
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biological source

human

Quality Segment

recombinant

expressed in E. coli

assay

≥98% (SDS-PAGE and HPLC)

form

lyophilized powder

potency

≤1.0 ng/mL

mol wt

17.6 kDa

packaging

pkg of 5 μg

storage condition

avoid repeated freeze/thaw cycles

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

UniProt accession no.

storage temp.

−20°C

Gene Information

human ... FLT3(2322)

General description

Mouse and human Flt-3 ligand share ~72% homology and both demonstrate cross-species activity.

Biochem/physiol Actions

Flt-3/Flk-2 Ligand (FL, or Flt-3L) is a transmembrane glycoprotein that binds and activates the Flt-3 receptor. Expression of Flt-3 is primarily restricted among hematopoietic cells to the most primitive progenitor cells.

Physical form

Lyophilized, 0.2 μm sterile filtered, with with 0.5x PBS.

Analysis Note

The biological activity is measured by its ability to stimulate the proliferation of human AML5 cells.


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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