F3917
毛喉素
For use in molecular biology applications
别名:
7β-乙酰氧基-1α,6β,9α-二羟基-8,13-环氧-半日花-14-EN-11-酮, 洋紫苏醇, 考福新
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关于此项目
经验公式（希尔记法）:
C22H34O7
化学文摘社编号:
分子量:
410.50
UNSPSC Code:
12352200
NACRES:
NA.52
PubChem Substance ID:
EC Number:
266-410-9
Beilstein/REAXYS Number:
1692716
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
biological source
Coleus forskohlii
Quality Segment
description
for activation of T cells
product line
BioReagent
assay
≥98% (HPLC)
form
powder
mol wt
410.50 g/mol
color
white to off-white
solubility
ethanol: soluble
suitability
suitable for inhibits interleukin 2 (IL-2) production in Jurkat cells
storage temp.
room temp
SMILES string
CC(=O)O[C@H]1[C@@H](O)[C@H]2C(C)(C)CC[C@H](O)[C@]2(C)[C@@]3(O)C(=O)C[C@@](C)(O[C@]13C)C=C
InChI
1S/C22H34O7/c1-8-19(5)11-14(25)22(27)20(6)13(24)9-10-18(3,4)16(20)15(26)17(28-12(2)23)21(22,7)29-19/h8,13,15-17,24,26-27H,1,9-11H2,2-7H3/t13-,15-,16-,17-,19-,20-,21+,22-/m0/s1
InChI key
OHCQJHSOBUTRHG-KGGHGJDLSA-N
General description
毛喉素是从Coleus forskohlii分离提取的细胞渗透双萜。
Biochem/physiol Actions
具有抗高血压、正性变力作用和腺苷酸环化酶活化特性的细胞通透性二萜类化合物。它的许多生物学作用是由于其对腺苷酸环化酶的激活以及由此而导致的细胞内cAMP浓度增加。毛喉素可影响钙电流并抑制MAP激酶。
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves