SMILES string
Cl.Cl.OCCN1CCN(CCCN2c3ccccc3Sc4ccc(cc24)C(F)(F)F)CC1
InChI
1S/C22H26F3N3OS.2ClH/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29;;/h1-2,4-7,16,29H,3,8-15H2;2*1H
InChI key
MBHNWCYEGXQEIT-UHFFFAOYSA-N
Gene Information
human ... DRD1(1812), DRD2(1813), HRH1(3269)
General description
Fluphenazine may be useful for the treatment of schizophrenia.
Application
Fluphenazine dihydrochloride has been used:
- to study its effects as a drug on glioblastoma (GBM) cells
- in fluorescence-activated cell sorting (FACS) analysis, sorting and single-cell stress-survival experiments
- to study its exposure effects on learning and memory in adult rats
Biochem/physiol Actions
D1/D2多巴胺受体拮抗剂;吩噻嗪类抗精神病药;H1组胺受体拮抗剂。
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Repr. 1A
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Principles of Psychopharmacology for Mental Health Professionals (2006)
Coupling phenotypic persistence to DNA damage increases genetic diversity in severe stress
Yaakov G, et al.
Nature ecology & evolution, 1(1), 0016-0016 (2017)
G Cai et al.
Molecular pharmacology, 56(5), 989-996 (1999-10-26)
The interaction of dopaminergic antagonists with the D(1A) dopamine receptor was assessed in PC2 cells that transiently express this receptor. The maximal binding and dissociation constants for the D(1A) dopamine receptor, using the ligand [(125)I]SCH23982 were 0.38 +/- 0.09 nM
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| F4765-5G | 04061832090832 |
| F4765-1G | 04061825982250 |

