F5178
Flavin-Containing Monooxygenase-5, Microsomes human
recombinant, expressed in baculovirus infected insect cells, buffered aqueous solution (2.5 mg in 100 mM Potassium Phosphate Buffer)
别名:
FMO-5
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recombinant
expressed in baculovirus infected insect cells
Quality Segment
form
buffered aqueous solution (2.5 mg in 100 mM Potassium Phosphate Buffer)
specific activity
≥700 units/mg protein
mol wt
55-60 kDa
packaging
vial of 2.5 mg
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... FMO5(2330)
Application
FMO5 is the only FMO isoform expressed in both adult and fetal human liver.
Biochem/physiol Actions
FMO′s are responsible for catalyzing the oxygenation of a variety of xenobiotic and drug compounds including environmental pollutants and carcinogens, which demonstrate a nucleophilic nitrogen, sulfur, selenium, and phosphorous-containing moiety associated with their respective oxides. These enzymes are classified as Phase I or oxidative drug metabolism enzymes. FMO5 is the only FMO isoform expressed in both adult and fetal human liver.
Physical form
Solution in 100 mM potassium phosphate buffer, pH 7.4.
Other Notes
methyl p-tolyl sulfide oxidase activity: One unit will catalyze the production of 1.0 picomole of methyl p-tolyl sulfoxide.
存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)