F5882
N-(3-[2-Furyl]acryloyl)-Ala-Lys
powder
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关于此项目
经验公式（希尔记法）:
C16H23N3O5
化学文摘社编号:
分子量:
337.37
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352204
MDL number:
产品名称
N-(3-[2-Furyl]acryloyl)-Ala-Lys, powder
InChI
1S/C16H23N3O5/c1-11(18-14(20)8-7-12-5-4-10-24-12)15(21)19-13(16(22)23)6-2-3-9-17/h4-5,7-8,10-11,13H,2-3,6,9,17H2,1H3,(H,18,20)(H,19,21)(H,22,23)/b8-7+/t11-,13-/m0/s1
SMILES string
C[C@H](NC(=O)\C=C\c1ccco1)C(=O)N[C@@H](CCCCN)C(O)=O
InChI key
BZUABSYGNBFITP-DDOQPMFUSA-N
assay
≥98% (TLC)
form
powder
color
white to light yellow
solubility
water: 50 mg/mL
soluble, clear to slightly hazy
storage temp.
−20°C
Quality Level
General description
Substrate for human plasma carboxypeptidase N.
Application
N-(3-[2-Furyl]acryloyl)-Ala-Lys has been used as a substrate in the carboxypeptidase B assay.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
B G Grimwood et al.
Analytical biochemistry, 170(1), 264-268 (1988-04-01)
A new high performance liquid chromatographic method has been developed for the determination of carboxypeptidase N activity which quantitates the furylacryloyl-alanine released by enzymatic cleavage of furylacryloyl-alanyl-lysine or furylacryloyl-alanyl-arginine. A short isocratic gradient elutes the substrate and product in less
Alejandra P Frasch et al.
Molecular and biochemical parasitology, 184(2), 63-70 (2012-05-12)
Metallocarboxypeptidases (MCP) of the M32 family of peptidases have been identified in a number of prokaryotic organisms but they are absent from eukaryotic genomes with the remarkable exception of those of trypanosomatids. The genome of Trypanosoma brucei, the causative agent
An improved spectrophotometric assay for human plasma carboxypeptidase N1.
T H Plummer et al.
Analytical biochemistry, 108(2), 348-353 (1980-11-01)
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