F7751

氟甲睾酮

Name: 氟甲睾酮
Brand: SIGMA

solid (photosensitive)

别名:

11β,17β-Dihydroxy-9α-fluoro-17α-methyl-4-androsten-3-one, 9α-Fluoro-11β,17β-dihydroxy-17α-methylandrost-4-en-3-one, 9α-Fluoro-11β-hydroxy-17α-methyltestosterone

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关于此项目

经验公式（希尔记法）:

C₂₀H₂₉FO₃

化学文摘社编号:

76-43-7

分子量:

336.44

UNSPSC Code:

51111800

PubChem Substance ID:

24894947

EC Number:

200-961-8

MDL number:

MFCD00010480

主要文件

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产品名称

氟甲睾酮, solid (photosensitive)

InChI key

YLRFCQOZQXIBAB-RBZZARIASA-N

InChI

1S/C20H29FO3/c1-17-8-6-13(22)10-12(17)4-5-15-14-7-9-19(3,24)18(14,2)11-16(23)20(15,17)21/h10,14-16,23-24H,4-9,11H2,1-3H3/t14-,15-,16-,17-,18-,19-,20-/m0/s1

SMILES string

[H][C@@]12CC[C@](C)(O)[C@@]1(C)C[C@H](O)[C@@]3(F)[C@@]2([H])CCC4=CC(=O)CC[C@]34C

biological source

Porcine pancreas
bovine milk (other parts like skeletal muscle/bile/bone/connective tissue/skin)
microbial (Mycobacterium sp.)

form

solid (photosensitive)

drug control

USDEA Schedule III; Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

color

white

solubility

H₂O: ≤0.5 mg/mL
45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 6.4 mg/mL
ethanol: 7.3 mg/mL

application(s)

forensics and toxicology
veterinary

shipped in

ambient

storage temp.

room temp

Gene Information

human ... AR(367), ESR1(2099), PRLR(5618)

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Biochem/physiol Actions

Fluoxymesterone is an androgen and anabolic steroid.

pictograms

GHS08

signalword

Warning

hcodes

H361

pcodes

P281

Hazard Classifications

Repr. 2

存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

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Toxic effects of anabolic-androgenic steroids in primary rat hepatic cell cultures.

A A Welder et al.

Journal of pharmacological and toxicological methods, 33(4), 187-195 (1995-08-01)

Hepatic complications in athletes and bodybuilders after abusing anabolic-androgenic steroids (AAS) have been reported. Hepatic injury, including cholestasis, peliosis hepatis, hyperplasia, and tumors, have been attributed to abuse of the 17 alpha-alkylated AAS. Some of these pathological conditions have been

Postsurgical adjuvant chemotherapy of stage II breast carcinoma with or without crossover to a non-cross-resistant regimen: a Cancer and Leukemia Group B study.

M Perloff et al.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 14(5), 1589-1598 (1996-05-01)

To compare two cyclophosphamide, methotrexate, fluorouracil, vincristine, and prednisone (CMFVP) regimens with a doxorubicin-based regimen--vinblastine, doxorubicin, thiotepa, and Halotestin (Upjohn, Kalamazoo, MI) (VATH)--in patients with stage II node-positive breast carcinoma. Nine hundred forty-five women were treated with a 6-week induction

Comparison of chemotherapy with chemohormonal therapy as first-line therapy for metastatic, hormone-sensitive breast cancer: An Eastern Cooperative Oncology Group study.

G W Sledge et al.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 18(2), 262-266 (2000-01-19)

Although hormonal therapy represents standard therapy for metastatic hormone-sensitive disease, many patients receive initial chemotherapy because of the location, bulk, or aggressiveness of their disease. It is uncertain whether simultaneous hormonal therapy provides additional benefit compared with chemotherapy alone. Eastern

Eastern Cooperative Oncology Group randomized trials of observation versus maintenance therapy for patients with metastatic breast cancer in complete remission following induction treatment.

G Falkson et al.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 16(5), 1669-1676 (1998-05-20)

To investigate the value of maintenance treatment for patients with metastatic breast cancer whose disease is in complete remission (CR). One hundred ninety-five women (141 eligible) whose disease was in CR or in CR except for bone metastases following six

Elucidation of urinary metabolites of fluoxymesterone by liquid chromatography-tandem mass spectrometry and gas chromatography-mass spectrometry.

Oscar J Pozo et al.

Journal of mass spectrometry : JMS, 43(3), 394-408 (2007-11-27)

The suitability of liquid chromatography tandem mass spectrometry (LC-MS/MS) and gas chromatography mass spectrometry (GC-MS) for the elucidation of fluoxymesterone metabolism has been evaluated. Electrospray ionization (ESI) and collision induced dissociation (CID) fragmentation in LC-MS/MS and electron impact spectra (EI)

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氟甲睾酮

solid (photosensitive)

选择尺寸

关于此项目

主要文件

属性

产品名称

InChI key

InChI

SMILES string

biological source

form

drug control

technique(s)

color

solubility

application(s)

shipped in

storage temp.

Gene Information

说明

Biochem/physiol Actions

安全信息

pictograms

signalword

hcodes

pcodes

Hazard Classifications

存储类别

wgk

flash_point_f

flash_point_c

ppe

法规信息

文件

分析证书(COA)

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