Anti-FURIN (106-120) antibody produced in rabbit

Furin is an endoprotease and belongs to the eukaryotic subtilisin family. It is synthesized as membrane-anchored endoproteases. Furin is colocalized mainly in the trans-golgi network although it is available in between this compartment and the cell surface to some lesser extent. It is the first identified proprotein convertase.

synthetic peptide corresponding to amino acids 106-120 of human FURIN

Anti-FURIN (106-120) antibody is suitable for western blot analysis at a dilution of 1:500-1:2,000.
Yale Center for High Throughput Cell Biology IF-tested antibodies. Each antibody is tested by immunofluorescence against HUVEC cells using the Yale HTCB IF protocol. To learn more about us and Yale Center for High Throughput Cell Biology partnership, visit sigma.com/htcb-if.

Furin plays a vital role in cleaving of a wide variety of proteins, including growth factors, serum proteins, including proteases of the blood-clotting and complement systems, matrix metalloproteinases, receptors, viral-envelope glycoproteins and bacterial exotoxins.

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide

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