Merck
CN

F8758

Sigma-Aldrich

叶酸

BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture, ≥97%

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别名:
戊基单谷氨酸, N-4-[(2-氨基-4-氧代-1,4-二氢-6-喋啶)甲氨基苯甲酰基]-L-谷氨酸, PteGlu, 维生素 M
经验公式(希尔记法):
C19H19N7O6
CAS号:
分子量:
441.40
Beilstein:
100781
EC 号:
MDL编号:
eCl@ss:
34058014
PubChem化学物质编号:
NACRES:
NA.75

生物来源

synthetic

质量水平

产品线

BioReagent

检测方案

≥97%

形式

powder

分子量

Mw 441.40 g/mol

技术

cell culture | insect: suitable
cell culture | mammalian: suitable
cell culture | plant: suitable

颜色

dark yellow

溶解性

1 M NaOH: soluble 50 mg/mL, clear to very slightly hazy, faintly yellow to dark yellow-orange

储存温度

room temp

SMILES字符串

NC(N1)=NC(C2=C1N=CC(CNC3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)=N2)=O

InChI

1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1

InChI key

OVBPIULPVIDEAO-LBPRGKRZSA-N

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一般描述

叶酸(FA)/蝶酰单谷氨酸 有助于阻断神经管缺陷(NTD)。

应用

叶酸已被用于:
  • 研究维生素和氨基酸对杂交瘤生长和单克隆抗体生成的影响
  • 用于细胞和治疗
  • 使用CRISPR/Cas基因编辑方法进行穿孔素基因打靶

生化/生理作用

叶酸的营养输送形式。叶酸及其衍生物是细胞内一碳代谢的必需介质。

储存分类代码

11 - Combustible Solids

WGK

WGK 1

个人防护装备

Eyeshields, Gloves, type N95 (US)


分析证书(COA)

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. What is the solubility of folic acid (Product No. F8758)?

    Product No. F8758 is soluble in 1 M NaOH (50 mg/mL). The free acid is only slightly soluble in water (0.01 mg/mL at 0 °C), and is insoluble in aqueous solutions below pH 5. It is soluble in sodium bicarbonate or sodium hydroxide solutions.

  6. What is the stability of folic acid (Product No. F8758) once in solution?  

    This product is photolabile and is inactivated by UV light. Alkaline solutions are reasonably stable in the dark, but heating will destroy both alkaline and acidic solutions.

  7. Is Product No. F8758, Folic Acid, tested for endotoxins?  

    No, Product No. F8758 has not been tested for endotoxins. This product has, however, been tested for use in mammalian cell culture and insect cell culture.

  8. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

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