FSL-biotin

All FSL constructs disperse in biocompatible media and spontaneously and stably incorporate into cell membranes. Cells modified with FSL constructs are known as kodecytes and usually maintain their normal vitality and functionality. FSL-biotin has been specifically designed to create biotinylated live cells (kodecytes) but can also be used to modify other hydrophobic surfaces including fixed cells, virions, and solid phase surfaces. Biotinylated kodecytes can be reacted with a variety of biotin binding protein constructs including fluorescent labeled avidin and avidinylated beads/solid surfaces.

All FSL constructs disperse in biocompatible media and spontaneously and stably incorporate into cell membranes. FSL-biotin has been specifically designed to create biotinylated live cells (kodecytes) but can also be used to modify other hydrophobic surfaces including fixed cells, virions, and solid phase surfaces.

FSL-biotin is a KODE^™ technology construct designed to label hydrophobic surfaces including living cells with biotin. All FSL constructs consist of three essential designable features: a functional component (F), a spacer (S), and a diacyl lipid (L). FSL-biotin is comprised of a monomer of biotin (vitamin B₇) representing F, conjugated to a maleimide-bearing carboxymethylglycine based linker (SC2) in turn conjugated to an activated adipate derivative of dioleoylphosphatidylethanolamine (L1).

KODE Constructs are supplied by KODE Biotech Materials Limited under license from KODE Biotech Limited.

KODE is a trademark of KODE Biotech Ltd.