G1049
聚-L-γ-谷氨酸 钠盐
suitable for drug transporter assays, Mol wt ≥750,000
别名:
γ-PGA
产品名称
聚-L-γ-谷氨酸 钠盐,
form
powder
mol wt
≥750,000
technique(s)
drug transporter assay: suitable
color
white to off-white
application(s)
cell analysis
storage temp.
−20°C
Quality Level
Application
高分子量聚-γ-谷氨酸（γPGA）被证明可以在C57BL/6小鼠中增加NK细胞介导的细胞毒性水平以及 INF-γ分泌。 已经评估了可生物降解的γ-PGA纳米颗粒作为抗原递送载体 以及递送流感病毒血凝素（HA）疫苗的应用。 γ-PGA的其他生命科学应用包括用于可生物降解的纤维和纳米纤维片、水凝胶和冷冻保护剂。
Other Notes
高分子量聚-γ-谷氨酸是一种谷氨酸聚合物，由α-氨基和γ-羧基之间的酰胺键连接。 γ-PGA是由芽孢杆菌发酵产生的。该亚基主要是L-异构体。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Shigefumi Okamoto et al.
Vaccine, 27(42), 5896-5905 (2009-08-04)
Adding poly(gamma-glutamic acid) nano-particles (gamma-PGA-NPs), a safe, natural material, to subcutaneous immunization with influenza virus hemagglutinin (HA) vaccine increases the protective immune responses against influenza virus in mice. Here, we examined whether intranasal administration of the HA vaccine with gamma-PGA-NPs
The utility of poly(γ-glutamic acid) nanoparticles as antigen delivery carriers in dendritic cell-based cancer immunotherapy.
Matsuo, K., et al.
Biological & Pharmaceutical Bulletin, 33, 2007-2007 (2010)
Preparation and evaluation of poly(γ-glutamic acid)-based anti-adhesion membranes.
Kim, Y.-A., et al.
Key Engineering Materials, 342, 225-225 (2007)
Haryoung Poo et al.
Chemistry & biodiversity, 7(6), 1555-1562 (2010-06-22)
Ultra-high-molecular-weight poly-gamma-glutamic acid (gamma-PGA) is a most promising biodegradable polymer that is produced by Bacillus subtilis (chungkookjang). Attractive properties of gamma-PGA are that it is water soluble, anionic, biodegradable, and edible. Development of gamma-PGA has pursued in terms of cosmetics/skin
Tae Woo Kim et al.
Journal of immunology (Baltimore, Md. : 1950), 179(2), 775-780 (2007-07-10)
We analyzed the in vivo tumor regression activity of high molecular mass poly-gamma-glutamate (gamma-PGA) from Bacillus subtilis sups. chungkookjang. C57BL/6 mice were orally administered 10-, 100-, or 2000-kDa gamma-PGA or beta-glucan (positive control), and antitumor immunity was examined. Our results
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持