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G1260

Gastrin II Sulfated

Name: Gastrin II Sulfated
Brand: SIGMA

≥95% (HPLC), suitable for ligand binding assays

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关于此项目

经验公式（希尔记法）:

C₉₇H₁₂₄N₂₀O₃₄S₂

化学文摘社编号:

19361-51-4

分子量:

2178.27

UNSPSC Code:

12352209

PubChem Substance ID:

24895054

NACRES:

NA.26

MDL number:

MFCD00133360

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属性

产品名称

Gastrin II Sulfated, ≥95% (HPLC)

Quality Level

200

assay

≥95% (HPLC)

form

powder

technique(s)

ligand binding assay: suitable

color

white

UniProt accession no.

P01350

storage temp.

−20°C

SMILES string

CSCCC(NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)CNC(=O)C(Cc3ccc(OS(O)(=O)=O)cc3)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(CCC(O)=O)NC(=O)C(CCC(O)=O)NC(=O)C(CCC(O)=O)NC(=O)C(CCC(O)=O)NC(=O)C(CC(C)C)NC(=O)C(Cc4c[nH]c5ccccc45)NC(=O)C6CCCN6C(=O)CNC(=O)C7CCC(=O)N7)C(=O)NC(CC(O)=O)C(=O)NC(Cc8ccccc8)C(N)=O

InChI

1S/C97H124N20O34S2/c1-49(2)39-68(114-95(145)71(43-54-46-100-59-18-11-9-16-57(54)59)116-97(147)73-19-12-37-117(73)76(120)48-102-85(135)60-24-30-74(118)104-60)93(143)110-65(29-35-81(129)130)91(141)109-64(28-34-80(127)128)90(140)108-63(27-33-79(125)126)89(139)107-62(26-32-78(123)124)88(138)106-61(25-31-77(121)122)87(137)103-50(3)84(134)113-69(41-52-20-22-55(23-21-52)151-153(148,149)150)86(136)101-47-75(119)105-70(42-53-45-99-58-17-10-8-15-56(53)58)94(144)111-66(36-38-152-4)92(142)115-72(44-82(131)132)96(146)112-67(83(98)133)40-51-13-6-5-7-14-51/h5-11,13-18,20-23,45-46,49-50,60-73,99-100H,12,19,24-44,47-48H2,1-4H3,(H2,98,133)(H,101,136)(H,102,135)(H,103,137)(H,104,118)(H,105,119)(H,106,138)(H,107,139)(H,108,140)(H,109,141)(H,110,143)(H,111,144)(H,112,146)(H,113,134)(H,114,145)(H,115,142)(H,116,147)(H,121,122)(H,123,124)(H,125,126)(H,127,128)(H,129,130)(H,131,132)(H,148,149,150)

InChI key

WSLIFCVCCVWYQQ-UHFFFAOYSA-N

Gene Information

human ... GAST(2520)

说明

Biochem/physiol Actions

Gastrin II and Gastrin I are peptide hormones involved in gastrointestinal processes such as the stimulation of gastric (HCl) release.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

新产品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

0000461101

0000461102

0000402673

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Cholecystokinin and gastrin induce cell contraction in pig ileum by interacting with different receptor subtypes.

A Botella et al.

Gastroenterology, 102(3), 779-786 (1992-03-01)

The aim of this study was to determine the cholecystokinin (CCK) receptor subtype involved in the direct myogenic effect of CCK on pig ileum. Smooth muscle cells were dispersed from pig ileum circular muscle layer and incubated in the presence

Facile solid-phase synthesis of sulfated tyrosine-containing peptides: Part II. Total synthesis of human big gastrin-II and its C-terminal glycine-extended peptide (G34-Gly sulfate) by the solid-phase segment condensation approach.

K Kitagawa et al.

Chemical & pharmaceutical bulletin, 49(8), 958-963 (2001-08-23)

Application of the fluoren-9-ylmethoxycarbonyl (Fmoc)-based solid-phase segment condensation approach to the preparation of sulfated peptides was investigated through the synthesis of human big gastrin-II, a 34-residue sulfated tyrosine [Tyr(SO3H)]-containing peptide. Highly acid-sensitive 2-chlorotrityl resin (Clt resin) was exclusively employed as

Gastrin stimulates Ca2+ mobilization and clonal growth in small cell lung cancer cells.

T Sethi et al.

Cancer research, 52(21), 6031-6035 (1992-11-01)

Gastrin has been postulated to be a physiological growth factor, but compelling in vitro evidence of this has been difficult to obtain. In the present study we investigated whether small cell lung carcinoma cell lines could provide a useful model

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全球贸易项目编号

货号	GTIN
G1260-.1MG	04061832820347