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Merck
CN

G1272

Sigma-Aldrich

Gentamicin

liquid, non-animal origin, suitable for cell culture, BioReagent

别名:

庆大霉素 C, 正泰霉素

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关于此项目

CAS Number:
EC 号:
MDL编号:
UNSPSC代码:
12352207
eCl@ss:
42020823
PubChem化学物质编号:
NACRES:
NA.76
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Product Name

庆大霉素 溶液, 10 mg/mL in deionized water, liquid, 0.1 μm filtered, BioReagent, suitable for cell culture

生物来源

microbial

质量水平

无菌性

0.1 μm filtered

产品线

BioReagent

表单

liquid

效能

10-12 mg per mL

浓度

10 mg/mL in deionized water

技术

cell culture | mammalian: suitable

杂质

endotoxin, tested

颜色

colorless to light yellow

抗生素抗菌谱

Gram-negative bacteria
Gram-positive bacteria
mycoplasma

作用机制

protein synthesis | interferes

储存温度

2-8°C

SMILES字符串

OS(O)(=O)=O.CN[C@@H]1[C@@H](O)[C@H](OC[C@]1(C)O)O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3O[C@H](CN)CC[C@H]3N)[C@@H]2O.CN[C@@H]4[C@@H](O)[C@H](OC[C@]4(C)O)O[C@H]5[C@H](N)C[C@H](N)[C@@H](O[C@H]6O[C@@H](CC[C@H]6N)[C@@H](C)N)[C@@H]5O.CN[C@H](C)[C@@H]7CC[C@@H](N)[C@H](O7)O[C@@H]8[C@@H](N)C[C@@H](N)[C@H](O[C@H]9OC[C@](C)(O)[C@H](NC)[C@H]9O)[C@H]8O

InChI

1S/C21H43N5O7.C20H41N5O7.C19H39N5O7.H2O4S/c1-9(25-3)13-6-5-10(22)19(31-13)32-16-11(23)7-12(24)17(14(16)27)33-20-15(28)18(26-4)21(2,29)8-30-20;1-8(21)12-5-4-9(22)18(30-12)31-15-10(23)6-11(24)16(13(15)26)32-19-14(27)17(25-3)20(2,28)7-29-19;1-19(27)7-28-18(13(26)16(19)24-2)31-15-11(23)5-10(22)14(12(15)25)30-17-9(21)4-3-8(6-20)29-17;1-5(2,3)4/h9-20,25-29H,5-8,22-24H2,1-4H3;8-19,25-28H,4-7,21-24H2,1-3H3;8-18,24-27H,3-7,20-23H2,1-2H3;(H2,1,2,3,4)/t9-,10-,11+,12-,13+,14+,15-,16-,17+,18-,19-,20-,21+;8-,9-,10+,11-,12+,13+,14-,15-,16+,17-,18-,19-,20+;8-,9+,10-,11+,12-,13+,14+,15-,16+,17+,18+,19-;/m110./s1

InChI key

RDEIXVOBVLKYNT-HDZPSJEVSA-N

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一般描述

化学结构:氨基糖苷类

应用

硫酸庆大霉素,是一种广谱抗生素,在分子生物学和细胞培养应用中作为选择剂(庆大霉素抗性基因)。该产品以10 mg/mL庆大霉素浓度在去离子水中配制,建议用于真核细胞培养,每升添加1毫升。

生化/生理作用

作用机制:庆大霉素可通过与核糖体的30S亚基结合来抑制蛋白质合成。

抗菌谱:包括革兰氏阴性和革兰氏阳性细菌,包括对于四环素,氯霉素,卡那霉素和粘菌素,某些特定假单胞菌菌株,变形杆菌属,StaphylococcusStreptococcus的抗性。

其他说明

庆大霉素是Micromonospora purpurea M. echinospora发酵后产生的氨基糖苷复合物。 它可以用来作为硫酸盐。 每摩尔庆大霉素基础有三个成分,每一个成分包含五份碱性氮,并且需要5份硫酸。

免责声明

该产品在37°C下可稳定5天,并在2-8°C下保存。

象形图

Health hazard

警示用语:

Danger

危险声明

危险分类

Resp. Sens. 1 - Skin Sens. 1

储存分类代码

12 - Non Combustible Liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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S K Knauer et al.
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抗生素杀灭曲线是一项剂量响应实验,通过逐渐增大施加在哺乳动物细胞中的备选抗生素剂量进行测定。

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