Name: Galanthamine hydrobromide from <I>Lycoris</I> sp.
Brand: SIGMA

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About This Item

经验公式（希尔记法）:

C₁₇H₂₁NO₃ · HBr

CAS Number:

1953-04-4

分子量:

368.27

EC 号:

217-780-5

MDL编号:

MFCD00067672

UNSPSC代码:

12352116

PubChem化学物质编号:

24895074

NACRES:

NA.32

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生物来源

plant (Ungeria victoris)

质量水平

100

方案

≥94% (HPLC)

表单

powder

mp

270 °C

溶解性

DMSO: soluble 10 mg/mL, clear, colorless
water: soluble 20 mg/mL, clear, colorless

储存温度

−20°C

SMILES字符串

Br[H].COc1ccc2CN(C)CC[C@@]34C=C[C@H](O)C[C@@H]3Oc1c24

InChI

1S/C17H21NO3.BrH/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17;/h3-6,12,14,19H,7-10H2,1-2H3;1H/t12-,14-,17-;/m0./s1

InChI key

QORVDGQLPPAFRS-XPSHAMGMSA-N

基因信息

human ... ACHE(43)

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一般描述

Galanthamine hydrobromide is a derivative of galanthamine, which is an anticholinestrase alkaloid derived from genus Lycoris (Amaryllidaceae) or snowdrop. This compound is used for the treatment of Alzheimer′s disease (AD).

应用

Galanthamine hydrobromide from Lycoris sp. has been used-

as an AChE (acetylcholinesterase) inhibitor and positive control in acetylcholinesterase assay performed to determine the activity of AChE
as a positive control in the screening of AChE inhibitors
as a positive control in AChE inhibitory assay performed to determine the AChE-inhibitory activities of pyrithione and related sulfur-containing pyridine N-oxides