生物来源
plant (Ungeria victoris)
质量水平
方案
≥94% (HPLC)
表单
powder
mp
270 °C
溶解性
DMSO: soluble 10 mg/mL, clear, colorless
water: soluble 20 mg/mL, clear, colorless
储存温度
−20°C
SMILES字符串
Br[H].COc1ccc2CN(C)CC[C@@]34C=C[C@H](O)C[C@@H]3Oc1c24
InChI
1S/C17H21NO3.BrH/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17;/h3-6,12,14,19H,7-10H2,1-2H3;1H/t12-,14-,17-;/m0./s1
InChI key
QORVDGQLPPAFRS-XPSHAMGMSA-N
基因信息
human ... ACHE(43)
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一般描述
Galanthamine hydrobromide is a derivative of galanthamine, which is an anticholinestrase alkaloid derived from genus Lycoris (Amaryllidaceae) or snowdrop. This compound is used for the treatment of Alzheimer′s disease (AD).
应用
Galanthamine hydrobromide from Lycoris sp. has been used-
- as an AChE (acetylcholinesterase) inhibitor and positive control in acetylcholinesterase assay performed to determine the activity of AChE
- as a positive control in the screening of AChE inhibitors
- as a positive control in AChE inhibitory assay performed to determine the AChE-inhibitory activities of pyrithione and related sulfur-containing pyridine N-oxides
生化/生理作用
Cholinesterase inhibitor; reverses scopolamine-induced amnesia; antimyasthenic.
包装
Bottomless glass bottle. Contents are inside inserted fused cone.
警示用语:
Danger
危险声明
预防措施声明
危险分类
Acute Tox. 3 Oral
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
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