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Merck
CN

G2262

γ-Glutamyltranspeptidase from porcine kidney

Type IV, 2.0-6.0 units/mg solid

别名:

γ-GT, γ-Glutamyltransferase, (5-Glutamyl)peptide:amino-acid 5-glutamyltransferase, GGTP

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关于此项目

化学文摘社编号:
UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
232-931-5
MDL number:
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产品名称

γ-Glutamyltranspeptidase from porcine kidney, Type IV, 2.0-6.0 units/mg solid

type

Type IV

form

powder

specific activity

2.0-6.0 units/mg solid

storage temp.

−20°C

Quality Level

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Analysis Note

Crude

Application

γ-Glutamyltranspeptidase is used in the food industry to improve the umami taste of soy sauce.

Biochem/physiol Actions

γ- Glutamyltranspeptidase cleaves theγ-glutamyl amide bond from glutathione and its S-conjugates to remove glutamate.

Other Notes

One unit will liberate 1.0 μmole of p-nitroaniline from L-γ-glutamyl-p-nitroanilide per min at pH 8.5 at 25°C.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

低风险生物材料
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Improving the umami taste of soy sauce by the addition of bacterial γ-glutamyltranspeptidase as a glutaminase to the fermentation mixture
K. Kijima & H. Suzuki
Enzyme and Microbial Technology, 41, 80-84 (2007)
S S Tate et al.
Molecular and cellular biochemistry, 39, 357-368 (1981-09-25)
gamma-Glutamyl transpeptidase catalyzes transfer of the gamma-glutamyl moiety of glutathione to amino acids, dipeptides, and to glutathione itself; the enzyme also catalyzes the hydrolysis of glutathione to glutamate and cysteinyl-glycine. This review deals with the tissue distribution and localization of
Stephanie Wickham et al.
The Biochemical journal, 450(3), 547-557 (2013-01-11)
GGT (γ-glutamyl transpeptidase) is an essential enzyme for maintaining cysteine homoeostasis, leukotriene synthesis, metabolism of glutathione conjugates and catabolism of extracellular glutathione. Overexpression of GGT has been implicated in many pathologies, and clinical inhibitors of GGT are under development for
γ-Glutamyl transferase and its role as a biomarker of systemic malignancies other than hepatocellular carcinomas.
Shailendra Kapoor
European journal of gastroenterology & hepatology, 25(3), 387-387 (2013-01-26)
Yumin Wang et al.
Archives of Iranian medicine, 16(2), 74-77 (2013-01-31)
Many studies have suggested that visfatin expression is closely related to the occurrence of insulin resistance (IR), while the precise role of visfatin in the regulation of IR in chronic hepatitis C (CHC) is not clear. We investigated fasting glucose

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