G2501
L-谷氨酸脱氢酶 来源于牛肝脏
Type I, ammonium sulfate suspension, ≥40 units/mg protein
别名:
L -GLDH, L -谷氨酸盐：NAD[P]+ 氧化还原酶（脱氨）, 谷氨酸脱氢酶 来源于牛肝脏
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关于此项目
化学文摘社编号:
UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
232-848-4
MDL number:
Specific activity:
≥40 units/mg protein
产品名称
L-谷氨酸脱氢酶 来源于牛肝脏, Type I, ammonium sulfate suspension, ≥40 units/mg protein
type
Type I
form
ammonium sulfate suspension
specific activity
≥40 units/mg protein
mol wt
310-350 kDa
UniProt accession no.
storage temp.
2-8°C
Quality Level
Gene Information
cow ... GLUD1(281785)
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Analysis Note
双缩脲法测蛋白
Biochem/physiol Actions
L-谷氨酸脱氢酶可催化谷氨酸转化成α-酮戊二酸。
这种酶的哺乳动物形式，包括这种牛形式，可以使用 NADP (H) 或 NAD (H) 作为辅酶。 L -谷氨酸脱氢酶在哺乳动物代谢中起着独特角色。该酶催化的逆向反应是氨与 α-淀粉结合的唯一途径。-α 的碳原子-因此，羧酸是哺乳动物中从头合成氨基酸的唯一来源。
牛酶的特点有三组属性：
L-谷氨酸脱氢酶催化谷氨酸转化为 α-酮戊二酸 。
牛酶的特点有三组属性：
- 具有可逆的浓度依赖性结合，产生较高分子量形式。
- 形成紧密的酶-还原型辅酶-底物三元复合物，其解离速率调节稳态反应速率。
- 表现出各种各样的影响，从结合的任何编号核苷酸修饰。
L-谷氨酸脱氢酶催化谷氨酸转化为 α-酮戊二酸 。
Other Notes
在25℃、pH 7.3、铵离子存在的条件下，一单位酶每分钟可将1.0 μmM α-酮戊二酸还原成 L-谷氨酸。
Physical form
2.0 M (NH4)2SO4 溶液混悬液
signalword
Danger
hcodes
pcodes
Hazard Classifications
Resp. Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
低风险生物材料
此项目有
Michisuke Yuzaki
The European journal of neuroscience, 32(2), 191-197 (2010-07-22)
Several C1q family members, especially the Cbln and C1q-like subfamilies, are highly and predominantly expressed in the central nervous system. Cbln1, a member of the Cbln subfamily, plays two unique roles at parallel fiber (PF)-Purkinje cell synapses in the cerebellum:
Cleanthe Spanaki et al.
Neurotoxicity research, 21(1), 117-127 (2011-11-01)
Glutamate dehydrogenase (GDH) catalyzes the reversible inter-conversion of glutamate to α-ketoglutarate and ammonia. High levels of GDH activity is found in mammalian liver, kidney, brain, and pancreas. In the liver, GDH reaction appears to be close-to-equilibrium, providing the appropriate ratio
Shanti Balasubramaniam et al.
Journal of pediatric endocrinology & metabolism : JPEM, 24(7-8), 573-577 (2011-09-22)
Hyperinsulinism-hyperammonemia syndrome (HI/HA) (OMIM 606762), the second most common form of congenital hyperinsulinism (CHI) is associated with activating missense mutations in the GLUD1 gene, which encodes the mitochondrial matrix enzyme, glutamate dehydrogenase (GDH). Patients present with recurrent symptomatic postprandial hypoglycemia
Mehran Karimi et al.
Seminars in thrombosis and hemostasis, 35(4), 426-438 (2009-07-15)
Factor XIII (FXIII) is a tetrameric zymogen (FXIII-A (2)B (2)) that is converted into an active transglutaminase (FXIIIa) by thrombin and Ca (2+) in the terminal phase of the clotting cascade. By cross-linking fibrin chains and alpha (2) plasmin inhibitor
Hyperinsulinism and hyperammonaemia syndrome and severe myoclonic epilepsy of infancy.
F Pérez Errazquin et al.
Neurologia (Barcelona, Spain), 26(4), 248-252 (2010-12-18)
商品
Instructions for working with enzymes supplied as ammonium sulfate suspensions
以硫酸铵悬浮液形式提供的酶的使用指南
相关内容
QC Methods
Product Information Sheet
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