biological source
bovine liver
Quality Level
type
Type II
form
glycerol solution (50%)
specific activity
≥35 units/mg protein
mol wt
310-350 kDa
UniProt accession no.
shipped in
wet ice
storage temp.
2-8°C
Gene Information
cow ... GLUD1(281785)
Application
L-谷氨酸脱氢酶催化异柠檬酸转化为 α-酮戊二酸和二氧化碳。
Biochem/physiol Actions
这种酶的哺乳动物形式,包括这种牛形式,可以使用 NADP (H) 或 NAD (H) 作为辅酶。 L -谷氨酸脱氢酶在哺乳动物代谢中起着独特角色。该酶催化的逆向反应是氨与 α-淀粉结合的唯一途径。-α 的碳原子-因此,羧酸是哺乳动物中从头合成氨基酸的唯一来源。
牛酶的特点有三组属性:
L-谷氨酸脱氢酶催化谷氨酸转化为 α-酮戊二酸 。
牛酶的特点有三组属性:
- 具有可逆的浓度依赖性结合,产生较高分子量形式。
- 形成紧密的酶-还原型辅酶-底物三元复合物,其解离速率调节稳态反应速率。
- 表现出各种各样的影响,从结合的任何编号核苷酸修饰。
L-谷氨酸脱氢酶催化谷氨酸转化为 α-酮戊二酸 。
Physical form
50%甘油溶液
Analysis Note
双缩脲法测定蛋白质。
Other Notes
在存在铵离子的情况下,在 pH 7.3,25°C 下,1 个单位的 α-酮戊二酸每分钟将以 1.0 μmol 的速率还原为 L-谷氨酸盐。
Still not finding the right product?
Explore all of our products under L-谷氨酸脱氢酶 来源于牛肝脏
存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
低风险生物材料
此项目有
商品
For use as a marker in SDS-PAGE; Albumin from chicken egg white, For use as a marker in SDS-PAGE; L-Lactic Dehydrogenase from rabbit muscle, Type XI, lyophilized powder, 600-1,200 units/mg protein
相关内容
QC Methods
Product Information Sheet
Probing the role of the residues in the active site of the transaminase from Thermobaculum terrenum.
Bezsudnova, et al.
PLoS ONE, 16, e0255098-e0255098 (2021)
Mariagrazia Grimaldi et al.
Human molecular genetics, 26(18), 3453-3465 (2017-09-16)
Congenital hyperinsulinism/hyperammonemia (HI/HA) syndrome gives rise to unregulated protein-induced insulin secretion from pancreatic beta-cells, fasting hypoglycemia and elevated plasma ammonia levels. Mutations associated with HI/HA were identified in the Glud1 gene, encoding for glutamate dehydrogenase (GDH). We aimed at identifying
S Vesce et al.
FEBS letters, 411(1), 107-109 (1997-07-07)
The mechanisms of HIV-1 neurotoxicity remain still undefined although the induction of signalling events and a modest inhibition of glutamate uptake induced by the envelope glycoprotein, gp120, have called attention to astrocytes. Here we demonstrate that the levels at which
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| G2626-20MG | 04061833629161 |
| G2626-500MG | 04061833629239 |
| G2626-50MG | 04061833629253 |
| G2626-100MG | 04061833629154 |