跳转至内容
Merck
CN

G2626

L-谷氨酸脱氢酶 来源于牛肝脏

Type II, 50% glycerol solution, ≥35 units/mg protein

别名:

L -GLDH, L -谷氨酸盐:NAD[P]+ 氧化还原酶(脱氨), 谷氨酸脱氢酶 来源于牛肝脏

登录 查看组织和合同定价。

选择尺寸


关于此项目

化学文摘社编号:
UNSPSC Code:
12352204
NACRES:
NA.54
MDL number:
Specific activity:
≥35 units/mg protein
Biological source:
bovine liver
技术服务
需要帮助?我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助
技术服务
需要帮助?我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

产品名称

L-谷氨酸脱氢酶 来源于牛肝脏, Type II, 50% glycerol solution, ≥35 units/mg protein

biological source

bovine liver

type

Type II

form

glycerol solution (50%)

specific activity

≥35 units/mg protein

mol wt

310-350 kDa

UniProt accession no.

shipped in

wet ice

storage temp.

2-8°C

Quality Level

Gene Information

cow ... GLUD1(281785)

正在寻找类似产品? 访问 产品对比指南

Analysis Note

双缩脲法测定蛋白质。

Application

L-谷氨酸脱氢酶催化异柠檬酸转化为 α-酮戊二酸和二氧化碳。

Biochem/physiol Actions

这种酶的哺乳动物形式,包括这种牛形式,可以使用 NADP (H) 或 NAD (H) 作为辅酶。 L -谷氨酸脱氢酶在哺乳动物代谢中起着独特角色。该酶催化的逆向反应是氨与 α-淀粉结合的唯一途径。-α 的碳原子-因此,羧酸是哺乳动物中从头合成氨基酸的唯一来源。

牛酶的特点有三组属性:
  • 具有可逆的浓度依赖性结合,产生较高分子量形式。
  • 形成紧密的酶-还原型辅酶-底物三元复合物,其解离速率调节稳态反应速率。
  • 表现出各种各样的影响,从结合的任何编号核苷酸修饰。

L-谷氨酸脱氢酶催化谷氨酸转化为 α-酮戊二酸 。

Other Notes

在存在铵离子的情况下,在 pH 7.3,25°C 下,1 个单位的 α-酮戊二酸每分钟将以 1.0 μmol 的速率还原为 L-谷氨酸盐。

Physical form

50%甘油溶液

存储类别

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

低风险生物材料
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

没有发现合适的版本?

如果您需要特殊版本,可通过批号或批次号查找具体证书。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

S Vesce et al.
FEBS letters, 411(1), 107-109 (1997-07-07)
The mechanisms of HIV-1 neurotoxicity remain still undefined although the induction of signalling events and a modest inhibition of glutamate uptake induced by the envelope glycoprotein, gp120, have called attention to astrocytes. Here we demonstrate that the levels at which
Probing the role of the residues in the active site of the transaminase from Thermobaculum terrenum.
Bezsudnova, et al.
PLoS ONE, 16, e0255098-e0255098 (2021)
Mariagrazia Grimaldi et al.
Human molecular genetics, 26(18), 3453-3465 (2017-09-16)
Congenital hyperinsulinism/hyperammonemia (HI/HA) syndrome gives rise to unregulated protein-induced insulin secretion from pancreatic beta-cells, fasting hypoglycemia and elevated plasma ammonia levels. Mutations associated with HI/HA were identified in the Glud1 gene, encoding for glutamate dehydrogenase (GDH). We aimed at identifying
Virginia Kroef et al.
eLife, 11 (2022-03-02)
The hexosamine biosynthetic pathway (HBP) produces the essential metabolite UDP-GlcNAc and plays a key role in metabolism, health, and aging. The HBP is controlled by its rate-limiting enzyme glutamine fructose-6-phosphate amidotransferase (GFPT/GFAT) that is directly inhibited by UDP-GlcNAc in a
Sabine Ruegenberg et al.
Nature communications, 12(1), 2176-2176 (2021-04-14)
The hexosamine pathway (HP) is a key anabolic pathway whose product uridine 5'-diphospho-N-acetyl-D-glucosamine (UDP-GlcNAc) is an essential precursor for glycosylation processes in mammals. It modulates the ER stress response and HP activation extends lifespan in Caenorhabditis elegans. The highly conserved

商品

For use as a marker in SDS-PAGE; Albumin from chicken egg white, For use as a marker in SDS-PAGE; L-Lactic Dehydrogenase from rabbit muscle, Type XI, lyophilized powder, 600-1,200 units/mg protein

相关内容

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持