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经验公式(希尔记法):
C17H19N3O4 · HBr
化学文摘社编号:
分子量:
410.26
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352204
MDL number:
产品名称
Gly-Pro-7-amido-4-甲基香豆素 氢溴酸盐, dipeptidylpeptidase IV substrate
InChI
1S/C17H19N3O4.BrH/c1-10-7-16(22)24-14-8-11(4-5-12(10)14)19-17(23)13-3-2-6-20(13)15(21)9-18;/h4-5,7-8,13H,2-3,6,9,18H2,1H3,(H,19,23);1H/t13-;/m0./s1
SMILES string
Br.CC1=CC(=O)Oc2cc(NC(=O)[C@@H]3CCCN3C(=O)CN)ccc12
InChI key
PASXTQMFJRHMLJ-ZOWNYOTGSA-N
assay
≥97% (TLC)
form
powder
solubility
water: 50 mg/mL, clear, colorless to light yellow
storage temp.
−20°C
Quality Level
Application
Gly-Pro-7-氨基-4-甲基香豆素氢溴酸盐已被用作测定 Allophylus cominia Sw 提取物二肽基肽酶 IV (DPPIV) 活性的底物。
General description
二肽基氨肽酶 IV 的底物。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Fluorescence assay of x-prolyl dipeptidyl-aminopeptidase activity with a new fluorogenic substrate.
T Kato et al.
Biochemical medicine, 19(3), 351-359 (1978-06-01)
In vitro anti-diabetic activity of flavonoids and pheophytins from Allophylus cominia Sw. on PTP1B, DPPIV, alpha-glucosidase and alpha-amylase enzymes
Semaan DG, et al.
Journal of Ethnopharmacology, 203, 39-46 (2017)
Muhammed Majeed et al.
Journal of the science of food and agriculture, 100(2), 509-516 (2019-09-06)
Emblica officinalis, known as amla in Ayurveda, has been used as a folk medicine to treat numerous pathological conditions, including diabetes. However, the novel extract of E. officinalis fruit extract (amla fruit extract, AFE, Saberry®) containing 100 g kg-1 β-glucogallin along with
Sandy Theysgeur et al.
Molecules (Basel, Switzerland), 26(1) (2021-01-06)
Like their owners, dogs and cats are more and more affected by overweight and obesity-related problems and interest in functional pet foods is growing sharply. Through numerous studies, fish protein hydrolysates have proved their worth to prevent and manage obesity-related
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