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Merck
CN

G3002

Gly-Pro

≥98%, suitable for ligand binding assays

别名:

glycyl-L-proline

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关于此项目

经验公式(希尔记法):
C7H12N2O3
化学文摘社编号:
分子量:
172.18
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.26
EC Number:
211-880-2
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产品名称

Gly-Pro,

assay

≥98%

Quality Level

form

solid

technique(s)

ligand binding assay: suitable

color

white

storage temp.

−20°C

SMILES string

NCC(N1[C@H](C(O)=O)CCC1)=O

InChI

1S/C7H12N2O3/c8-4-6(10)9-3-1-2-5(9)7(11)12/h5H,1-4,8H2,(H,11,12)

InChI key

KZNQNBZMBZJQJO-UHFFFAOYSA-N

Application


  • [(68)Ga]Ga-DOTA-GPFAPI-04与[(18)F]F-FDG在实体瘤患者中的诊断效果对比:一项前瞻性临床研究的结果。:该研究探讨了多肽成像剂(特别是[(68)Ga]Ga-DOTA-GPFAPI-04)中Gly-Pro的使用,结果表明与传统成像模式相比,Gly-Pro 在检测实体瘤方面具有更优越的诊断性能,为癌症诊断和监测提供了新途径(Yuan et al., 2024)。

  • 了解抗高血压肽 Asn-Cys-Trp 的跨上皮转运和跨层扩散:Caco-2细胞单层和DPPC模型膜的见解。:该研究证明了Gly-Pro在研究抗高血压肽的吸收和代谢稳定性方面的实用性,为了解其药代动力学行为和改进给药策略提供了重要依据(Wu et al., 2024)。



pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Poonam Kalhotra et al.
Biomolecules, 10(2) (2020-02-23)
Diabetes mellitus is a severe health problem in Mexico, and its prevalence is increasing exponentially every year. Recently, DPP-4 (dipeptidyl peptidase-4) inhibitors have become attractive oral anti-hyperglycemic agents to reduce the pathology of diabetes. Gliptin's family, such as sitagliptin, vildagliptin
E Berardesca et al.
The British journal of dermatology, 126(2), 193-195 (1992-02-01)
A case is reported of a 15-year-old boy with prolidase deficiency and marked urinary excretion of the iminodipeptide gly-pro. Prolidase activity of erythrocytes against substrate glycyl-proline was deficient, but after blood transfusions this was increased to 15.7% of donor activity
Min Fey Chek et al.
Scientific reports, 7(1), 5312-5312 (2017-07-15)
Polyhydroxyalkanoate (PHA) is a promising candidate for use as an alternative bioplastic to replace petroleum-based plastics. Our understanding of PHA synthase PhaC is poor due to the paucity of available three-dimensional structural information. Here we present a high-resolution crystal structure



全球贸易项目编号

货号GTIN
G3002-10G04061838354587