G4626
L -氧化谷胱甘肽 二钠盐
≥98%, suitable for HPLC
别名:
GSSG
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关于此项目
经验公式（希尔记法）:
C20H30N6Na2O12S2
化学文摘社编号:
分子量:
656.59
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26
Beilstein/REAXYS Number:
6265389
产品名称
L -氧化谷胱甘肽 二钠盐, ≥98%, powder
SMILES string
[Na+].[Na+].N[C@@H](CCC(=O)N[C@@H](CSSC[C@H](NC(=O)CC[C@H](N)C([O-])=O)C(=O)NCC(O)=O)C(=O)NCC([O-])=O)C(O)=O
InChI
1S/C20H32N6O12S2.2Na/c21-9(19(35)36)1-3-13(27)25-11(17(33)23-5-15(29)30)7-39-40-8-12(18(34)24-6-16(31)32)26-14(28)4-2-10(22)20(37)38;;/h9-12H,1-8,21-22H2,(H,23,33)(H,24,34)(H,25,27)(H,26,28)(H,29,30)(H,31,32)(H,35,36)(H,37,38);;/q;2*+1/p-2/t9-,10-,11-,12-;;/m0../s1
InChI key
DRFILBXQKYDTFW-JIWRMXRASA-L
assay
≥98%
form
powder
technique(s)
HPLC: suitable
impurities
ethanol, essentially free
color
white to off-white
storage temp.
−20°C
Quality Level
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Application
L-谷胱甘肽氧化二钠盐已用于5,5′-二硫代双-（2-硝基苯甲酸）（DTNB）/谷胱甘肽还原酶再循环法，以测定血浆或组织的谷胱甘肽水平。它还可用于NADPH依赖性谷胱甘肽二硫化物还原检测。
Biochem/physiol Actions
氧化的L-谷胱甘肽常在体内作为测量氧化应激的指示剂。氧化的L-谷胱甘肽可通过各种还原系统转化为L-谷胱甘肽。
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
动植物源性产品
此项目有
Dietary methionine can sustain cytosolic redox homeostasis in the mouse liver
Sofi Eriksson
Nature Communications (2015)
Oxidized forms of glutathione in peripheral blood as biomarkers of oxidative stress.
Rossi R
Clinical Chemistry, 52(7), 1406-1414 (2006)
Methods for the Determination of Plasma or Tissue Glutathione Levels
Trent E, et.al
Methods in Molecular Biology, 889, 315-324 (2012)
S K Tandon et al.
Toxicology letters, 145(3), 211-217 (2003-10-29)
The influence of an antioxidant agent such as N-acetyl cysteine (NAC) or mannitol on the cadmium chelating ability of monoisoamyl 2,3-dimercaptosuccinate (MiADMS) was investigated in cadmium pre-exposed rats. This ester of 2,3-dimercaptosuccinic acid (DMSA), an accepted drug for lead poisoning
Trent E Tipple et al.
Methods in molecular biology (Clifton, N.J.), 889, 315-324 (2012-06-07)
We present two different methods for determining levels of glutathione in complex biological samples and plasma. The DTNB/GR enzyme recycling method is sensitive and requires no specialized equipment. The HPLC method is particularly useful for situations in which sample amounts
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