G5013
G 418 二硫酸盐
potency: ≥720 μg per mg (dried basis)
别名:
抗生素G418
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关于此项目
经验公式（希尔记法）:
C20H40N4O10 · 2H2SO4
CAS Number:
分子量:
692.71
MDL编号:
UNSPSC代码:
51102829
PubChem化学物质编号:
NACRES:
NA.85
表单
powder
质量水平
效能
≥720 μg per mg (dried basis)
颜色
white to off-white
溶解性
H2O: 100 mg/mL
抗生素抗菌谱
Gram-negative bacteria
作用机制
protein synthesis | interferes
储存温度
2-8°C
SMILES字符串
OS(O)(=O)=O.OS(O)(=O)=O.CN[C@H]1[C@H](O)[C@@H](OC[C@@]1(C)O)O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3O[C@H]([C@H](C)O)[C@@H](O)[C@H](O)[C@H]3N)[C@@H]2O
InChI
1S/C20H40N4O10.2H2O4S/c1-6(25)14-11(27)10(26)9(23)18(32-14)33-15-7(21)4-8(22)16(12(15)28)34-19-13(29)17(24-3)20(2,30)5-31-19;2*1-5(2,3)4/h6-19,24-30H,4-5,21-23H2,1-3H3;2*(H2,1,2,3,4)/t6?,7-,8+,9+,10+,11-,12-,13-,14+,15+,16-,17-,18+,19-,20+;;/m0../s1
InChI key
UHEPSJJJMTWUCP-NKCAIAFTSA-N
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一般描述
化学结构：氨基糖苷类
制备说明
G418粉末可以100 mg/mL溶于水。
免责声明
本品在2-8°C可稳定储存三年。储备水溶液可在-20至-70 °C稳定储存约6个月。
警示用语：
Danger
危险声明
危险分类
Resp. Sens. 1 - Skin Sens. 1
储存分类代码
11 - Combustible Solids
WGK
WGK 3
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
监管及禁止进口产品
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Yoshie Tange et al.
PLoS genetics, 8(6), e1002776-e1002776 (2012-06-28)
To identify the genes required to sustain aneuploid viability, we screened a deletion library of non-essential genes in the fission yeast Schizosaccharomyces pombe, in which most types of aneuploidy are eventually lethal to the cell. Aneuploids remain viable for a
Triplet imaging of oxygen consumption during the contraction of a single smooth muscle cell (A7r5).
Matthias Geissbuehler et al.
Advances in experimental medicine and biology, 737, 263-268 (2012-01-20)
Alexandra L Petrache et al.
Frontiers in cellular neuroscience, 14, 568194-568194 (2020-12-03)
Selective negative allosteric modulators (NAMs), targeting α5 subunit-containing GABAA receptors (GABAARs) as potential therapeutic targets for disorders associated with cognitive deficits, including Alzheimer's disease (AD), continually fail clinical trials. We investigated whether this was due to the change in the
Terezie Imrichova et al.
Aging, 11(17), 7206-7235 (2019-09-08)
Diverse stress insults trigger interactions of PML with nucleolus, however, the function of these PML nucleolar associations (PNAs) remains unclear. Here we show that during induction of DNA damage-induced senescence in human non-cancerous cells, PML accumulates at the nucleolar periphery
Luis M Molinos-Albert et al.
Retrovirology, 11, 44-44 (2014-06-10)
The MPER region of the HIV-1 envelope glycoprotein gp41 is targeted by broadly neutralizing antibodies. However, the localization of this epitope in a hydrophobic environment seems to hamper the elicitation of these antibodies in HIV infected individuals.We have quantified and
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