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Merck
CN

G5386

Sigma-Aldrich

甘氨酸-甘氨酸-酪氨酸-精氨酸

powder, ≥97% (HPLC)

别名:

GGYR, Glycyl-glycyl-tyrosyl-arginine

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关于此项目

经验公式(希尔记法):
C19H29N7O6
化学文摘社编号:
分子量:
451.48
MDL编号:
UNSPSC代码:
12352204
PubChem化学物质编号:
NACRES:
NA.83
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产品名称

甘氨酸-甘氨酸-酪氨酸-精氨酸, ≥97% (HPLC)

生物来源

synthetic (organic)

质量水平

方案

≥97% (HPLC)

表单

powder

溶解性

water: 2 mg/mL, clear, colorless

储存温度

−20°C

SMILES字符串

NCC(=O)NCC(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CCCNC(N)=N)C(O)=O

InChI

1S/C19H29N7O6/c20-9-15(28)24-10-16(29)25-14(8-11-3-5-12(27)6-4-11)17(30)26-13(18(31)32)2-1-7-23-19(21)22/h3-6,13-14,27H,1-2,7-10,20H2,(H,24,28)(H,25,29)(H,26,30)(H,31,32)(H4,21,22,23)

InChI key

FJPHHBGPPJXISY-UHFFFAOYSA-N

应用

甘氨酸-甘氨酸-酪氨酸-精氨酸(Gly-Gly-Tyr-Arg)可用于:
  • 二甲氧基磷酸酪氨酸加合物合成,用于确定二乙氧基磷酸酪氨酸(depY)单克隆抗体是否能区分二甲氧基磷酸酪氨酸和二乙氧基磷酸酪氨酸
  • 接枝到软性聚丙烯酰胺,通过十二烷基硫酸钠-聚丙烯酰胺凝胶电泳(SDS-PAGE)高分辨率分离肽段
  • 作为模式肽与3,3-二硫代双(磺基琥珀酰亚胺丙酸酯)(DTSSP)反应,分析DTSSP和类似交联剂的化学性质

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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A J Kettle
FEBS letters, 379(1), 103-106 (1996-01-22)
Hypochlorous acid chlorinates tyrosyl residues in small peptides to produce chlorotyrosine. Detection of chlorotyrosine has the potential to unequivocally identify the contribution hypochlorous acid makes to inflammation. I have developed a selective and sensitive HPLC assay for measuring chlorotyrosine. When
Catherine L Swaim et al.
Journal of the American Society for Mass Spectrometry, 15(5), 736-749 (2004-05-04)
Synthetic cross-linking reagents, such as 3,3'-dithiobis(sulfosuccinimidyl propionate), DTSSP, can react with sidechains of amino acids that are within close proximity. Identification of cross-linked residues provides insight into the folded structures of proteins. However, analysis of proteolytic digests of proteins cross-linked
Xin Ying et al.
Food research international (Ottawa, Ont.), 141, 110148-110148 (2021-03-02)
Soy peptide solution (40%, w/w) was successfully encapsulated in a W1/O/W2 double emulsion produced by a two-step emulsification process. Polyglycerol polyricinoleate (PGPR) was found to be an effective inner emulsifier compared to Span 60 and lecithin to produce stable W1/O
N Belcheva et al.
Journal of biomaterials science. Polymer edition, 9(3), 207-226 (1998-04-29)
A new synthetic approach has been applied to obtain novel di-, tetra-, and (multi)-peptide containing polymer conjugates in quantitative yields with a high degree of conjugation. Bis-(N-hydroxysuccinimidyl) esters of PEG (Mw = 200, 600, 1400, 2000, and 3400) were synthesized
M Shimizu et al.
Peptides, 18(5), 681-687 (1997-01-01)
The transepithelial transport of oligopeptides (of more than 4 residues) was studied by using human intestinal Caco-2 cell monolyers. The susceptibility to the brush-border peptidases was observed to be one of the primary factors which decide the transport rate. The

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