G5537
甘油醛-3-磷酸脱氢酶 来源于面包酵母（酿酒酵母）
lyophilized powder, 70-140 units/mg protein
别名:
D-甘油醛-3-磷酸:NAD+ 氧化还原酶（磷酸化）, GAPDH
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关于此项目
化学文摘社编号:
UNSPSC Code:
12352204
EC Number:
232-609-4
MDL number:
Specific activity:
70-140 units/mg protein
form
lyophilized powder
specific activity
70-140 units/mg protein
composition
Protein, 30-70% biuret
foreign activity
3-Phosphoglyceric phosphokinase ≤0.05%
storage temp.
−20°C
Quality Level
Biochem/physiol Actions
甘油醛-3-磷酸脱氢酶催化3-醛甘油醛向1,3-双磷酸甘油酯的转化，作为糖酵解的一部分。 它也被证明在凋亡启动、转录激活和内质网向高尔基囊泡的穿梭中起作用 <<<,New> >>。
Physical form
用海藻糖、柠檬酸盐和DTT稳定的冻干的无硫酸盐粉末。 对于需要低硫酸盐的系统很有用。
Other Notes
在25°C的pH值为7.6的情况下，在具有3-磷酸甘油磷酸激酶的偶联系统中，每单位将每分钟将1.0μmol的3-磷酸甘油酯还原为D-甘油醛3-磷酸。
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
常规特殊物品
此项目有
Lei Tong et al.
The Journal of biological chemistry, 284(17), 11256-11266 (2009-03-03)
Although the classical redox functions of co-enzyme NAD(+) are firmly established in metabolism, there are numerous enzymes that catalyze cleavage of NAD(+) to yield free ADP-ribose (ADPr) or related metabolites, whose functions remain largely unknown. Here we show that the
A Tarze et al.
Oncogene, 26(18), 2606-2620 (2006-10-31)
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a pleiotropic enzyme that is overexpressed in apoptosis and in several human chronic pathologies. Here, we report that the protein accumulates in mitochondria during apoptosis, and induces the pro-apoptotic mitochondrial membrane permeabilization, a decisive event of
Pablo Moreno-Acosta et al.
Anticancer research, 32(10), 4319-4325 (2012-10-13)
The aim of this study was to evaluate the predictive utility of Insulin-like growth factor-1 receptor (IGF1R), IGF1, IGF2, Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) and of hemoglobin levels for tumor response to exclusive radiotherapy, in patients with locally advanced Human papillomavirus
Bing Fang et al.
Biochimie, 95(2), 251-257 (2012-09-27)
siRNA is promising in anti-tumor therapy. The main challenge is lack of tumor-specific intracellular delivery. In this study, a 6 amino acids peptide (A1) with high affinity for vascular endothelial growth factor receptor-1 (VEGFR1) was conjugated with a cell penetrating
Milan Jirků et al.
The Journal of eukaryotic microbiology, 59(6), 537-547 (2012-08-01)
Several new species of trypanosomatids (Euglenozoa, Kinetoplastea, Trypanosomatidae), isolated from the intestines of Neotropical insects (Heteroptera), were genotyped on the basis of spliced leader RNA, and also defined phylogenetically using gene sequences of small subunit ribosomal RNA and glycosomal glyceraldehyde
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