G5640
Globulins Cohn fraction II, III 来源于山羊
别名:
Vitamin D binding protein
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关于此项目
Form:
lyophilized powder
Assay:
73-90% protein basis (biuret)
Biological source:
goat
biological source
goat
Quality Segment
assay
73-90% protein basis (biuret)
form
lyophilized powder
composition
Protein, 73-90% biuret
solubility
H2O: soluble 25 mg/mL
storage temp.
2-8°C
General description
Vitamin D binding protein (DBP) is a polymorphic protein that specifically binds to vitamin D and its metabolites. This protein belongs to the albuminoid family and is highly conserved among vertebrates. The gene encoding DBP is mapped to human chromosome 4q11-q13. It is predominantly produced in the liver and is also expressed in the kidney, endocrine pancreatic cells, fat cells, and testis.
Application
Globulins were used in Biotin/avidin formulations.
Biochem/physiol Actions
Vitamin D binding protein (DBP) specifically binds and transports vitamin D and its metabolites with high affinity. It promotes fibrillar actin clearance by binding to actin monomers. DBP also binds to unsaturated fatty acids, megalin-cubilin receptor complex, the membrane of leukocytes, and the activation of the complement C5 system. The levels of DBP indicate the free concentration of all vitamin D metabolites. Decreased levels of serum DBP are observed in liver diseases, nephrotic syndrome, malnutrition, severe acute trauma, or disease.
Physical form
Lyophilized powder containing NaCl
Other Notes
Primarily γ-globulins
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable