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G5923

8-姜酚

Name: 8-姜酚
Brand: SIGMA

别名:

8-姜辣醇, 8-姜酮醇

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关于此项目

经验公式（希尔记法）:

C₁₉H₃₀O₄

化学文摘社编号:

23513-08-8

分子量:

322.44

UNSPSC Code:

12352205

NACRES:

NA.25

PubChem Substance ID:

329799947

MDL number:

MFCD00877794

Beilstein/REAXYS Number:

2059802

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属性

color

white to yellow

Quality Level

200

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

−20°C

SMILES string

CCCCCCC[C@H](O)CC(=O)CCc1ccc(O)c(OC)c1

InChI

1S/C19H30O4/c1-3-4-5-6-7-8-16(20)14-17(21)11-9-15-10-12-18(22)19(13-15)23-2/h10,12-13,16,20,22H,3-9,11,14H2,1-2H3/t16-/m0/s1

InChI key

BCIWKKMTBRYQJU-INIZCTEOSA-N

说明

Biochem/physiol Actions

8-姜酚是存在于生姜 (Zingiber officinale) 中的具有抗炎和抗氧化活性的生物活性化合物。

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pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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Identification of serotonin 5-HT1A receptor partial agonists in ginger.

Andreas Nievergelt et al.

Bioorganic & medicinal chemistry, 18(9), 3345-3351 (2010-04-07)

Animal studies suggest that ginger (Zingiber officinale Roscoe) reduces anxiety. In this study, bioactivity-guided fractionation of a ginger extract identified nine compounds that interact with the human serotonin 5-HT(1A) receptor with significant to moderate binding affinities (K(i)=3-20 microM). [(35)S]-GTP gamma

Regioselective glucuronidation of gingerols by human liver microsomes and expressed UDP-glucuronosyltransferase enzymes: reaction kinetics and activity correlation analyses for UGT1A9 and UGT2B7.

Zhufeng Wu et al.

The Journal of pharmacy and pharmacology, 67(4), 583-596 (2014-12-17)

To determine the reaction kinetics for regioselective glucuronidation of gingerols (i.e. 6-, 8- and 10-gingerol) by human liver microsomes and expressed UDP-glucuronosyltransferase (UGT) enzymes, and to identify the main UGT enzymes involved in regioselective glucuronidation of gingerols. The rates of

Chemical profiling and quantification of Gua-Lou-Gui-Zhi decoction by high performance liquid chromatography/quadrupole-time-of-flight mass spectrometry and ultra-performance liquid chromatography/triple quadrupole mass spectrometry.

Wen Xu et al.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 986-987, 69-84 (2015-02-25)

Gua-Lou-Gui-Zhi decoction (GLGZD) is a classical formula of traditional Chinese medicine, which has been commonly used to treat dysfunction after stroke, epilepsy and spinal cord injury. In this study, a systematic method was established for chemical profiling and quantification analysis

全球贸易项目编号

货号	GTIN
G5923-10MG	04061832408170
G5923-5MG	04061832408187