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Merck
CN

G6019

甘油醛-3-磷酸脱氢酶 来源于人类红细胞

lyophilized powder, 50-150 units/mg protein

别名:

D-甘油醛-3-磷酸:NAD+ 氧化还原酶(磷酸化), GAPDH

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化学文摘社编号:
MDL编号:
UNSPSC代码:
12352204
NACRES:
NA.54
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表单

lyophilized powder

质量水平

比活

50-150 units/mg protein

组成

Protein, 40-70% biuret

UniProt登记号

异质活性

3-Phosphoglyceric phosphokinase ≤2%

储存温度

−20°C

基因信息

human ... GAPDH(2597)

相关类别

生化/生理作用

甘油醛-3-磷酸脱氢酶可催化甘油醛-3-磷酸转化为1,3-双磷酸甘油酸酯,这是糖酵解的一部分。它也被证明在凋亡的启动、转录激活和内质网向高尔基囊泡的穿梭中起作用<<<18,New>>>。

外形

含柠檬酸钠缓冲盐的冻干粉

其他说明

在具有3-磷酸甘油酸磷酸激酶的偶联系统中,在 pH 7.6、25℃ 条件下,一单位每分钟可将 1.0μmole的3-磷酸甘油酯减少为D-甘油醛3-磷酸。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

高风险级别生物产品--人源产品
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历史批次信息供参考:

分析证书(COA)

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Bing Fang et al.
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Irina A Sevostyanova et al.
Biochemical and biophysical research communications, 427(3), 649-653 (2012-10-03)
Sperm-specific glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDS) is normally expressed only in sperms, but not in somatic tissues. Analysis of the expression of GAPDS mRNA in different cancer cell lines shows that the content of GAPDS mRNA is enhanced in some
Tina C Albershardt et al.
Journal of immunological methods, 384(1-2), 196-199 (2012-08-14)
Normalization to a reference gene is the method of choice for quantitative PCR analysis. The stability of reference genes is critical for accurate gene expression analysis, as significant variations in reference gene expression can alter experimental results and conclusions. In
Yuki Ikeda et al.
Archives of biochemistry and biophysics, 528(2), 141-147 (2012-09-25)
Cyclooxygenase (COX)-2 is an inducible inflammatory protein whose expression is partially regulated at the post-transcriptional level. We investigated whether glyceraldehyde-3-phosphate dehydrogenase (GAPDH) binds to the AU-rich element (ARE) of COX-2 mRNA for its degradation. Knockdown of GAPDH in hepa1c1c7 cells
Chiaki Inadomi et al.
Biochemical and biophysical research communications, 425(3), 656-661 (2012-08-01)
There is increasing evidence demonstrating that glutaredoxin 1 (GRX1), a cytosolic enzyme responsible for the catalysis of protein deglutathionylation, plays distinct roles in inflammation and apoptosis by inducing changes in the cellular redox system. In this study, we investigated whether

商品

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Warburg effect enhances glucose to lactate conversion in tumor cells, regardless of oxygen levels; impacting cancer metabolism since 1924.

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