G6019
甘油醛-3-磷酸脱氢酶 来源于人类红细胞
lyophilized powder, 50-150 units/mg protein
别名:
D-甘油醛-3-磷酸:NAD+ 氧化还原酶（磷酸化）, GAPDH
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关于此项目
化学文摘社编号:
UNSPSC Code:
12352204
NACRES:
NA.54
MDL number:
Specific activity:
50-150 units/mg protein
form
lyophilized powder
specific activity
50-150 units/mg protein
composition
Protein, 40-70% biuret
UniProt accession no.
foreign activity
3-Phosphoglyceric phosphokinase ≤2%
storage temp.
−20°C
Quality Level
Gene Information
human ... GAPDH(2597)
相关类别
Biochem/physiol Actions
甘油醛-3-磷酸脱氢酶可催化甘油醛-3-磷酸转化为1,3-双磷酸甘油酸酯，这是糖酵解的一部分。它也被证明在凋亡的启动、转录激活和内质网向高尔基囊泡的穿梭中起作用<<<18,New>>>。
Physical form
含柠檬酸钠缓冲盐的冻干粉
Other Notes
在具有3-磷酸甘油酸磷酸激酶的偶联系统中，在 pH 7.6、25℃ 条件下，一单位每分钟可将 1.0μmole的3-磷酸甘油酯减少为D-甘油醛3-磷酸。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
高风险级别生物产品--人源产品
此项目有
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Warburg effect enhances glucose to lactate conversion in tumor cells, regardless of oxygen levels; impacting cancer metabolism since 1924.
本页面介绍了一篇有关瓦博格效应的文章，以及其如何能够在正常氧气水平下，增强肿瘤细胞中葡萄糖向乳酸的转化。Otto Heinrich Warburg在1924年证明，癌细胞显示出对糖酵解的依赖性增加，以满足他们的能量需求，无论是否有充足的氧气存在。
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