Merck
CN

G6019

Sigma-Aldrich

甘油醛-3-磷酸脱氢酶 来源于人类红细胞

lyophilized powder, 50-150 units/mg protein

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别名:
D-甘油醛-3-磷酸:NAD+ 氧化还原酶(磷酸化), GAPDH
CAS号:
MDL编号:
NACRES:
NA.54

形式

lyophilized powder

质量水平

比活

50-150 units/mg protein

组成

Protein, 40-70% biuret

UniProt登记号

异质活性

3-Phosphoglyceric phosphokinase ≤2%

储存温度

−20°C

基因信息

human ... GAPDH(2597)

生化/生理作用

甘油醛-3-磷酸脱氢酶可催化甘油醛-3-磷酸转化为1,3-双磷酸甘油酸酯,这是糖酵解的一部分。它也被证明在凋亡的启动、转录激活和内质网向高尔基囊泡的穿梭中起作用<<<18,New>>>。

单位定义

在具有3-磷酸甘油酸磷酸激酶的偶联系统中,在 pH 7.6、25℃ 条件下,一单位每分钟可将 1.0μmole的3-磷酸甘油酯减少为D-甘油醛3-磷酸。

外形

含柠檬酸钠缓冲盐的冻干粉

抑制剂

产品编号
说明
价格

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品

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商品

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We presents an article about the Warburg effect, and how it is the enhanced conversion of glucose to lactate observed in tumor cells, even in the presence of normal levels of oxygen. Otto Heinrich Warburg demonstrated in 1924 that cancer cells show an increased dependence on glycolysis to meet their energy needs, regardless of whether they were well-oxygenated or not.

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