G6019
甘油醛-3-磷酸脱氢酶 来源于人类红细胞
lyophilized powder, 50-150 units/mg protein
别名:
D-甘油醛-3-磷酸:NAD+ 氧化还原酶（磷酸化）, GAPDH
表单
lyophilized powder
质量水平
比活
50-150 units/mg protein
组成
Protein, 40-70% biuret
UniProt登记号
异质活性
3-Phosphoglyceric phosphokinase ≤2%
储存温度
−20°C
基因信息
human ... GAPDH(2597)
相关类别
生化/生理作用
甘油醛-3-磷酸脱氢酶可催化甘油醛-3-磷酸转化为1,3-双磷酸甘油酸酯，这是糖酵解的一部分。它也被证明在凋亡的启动、转录激活和内质网向高尔基囊泡的穿梭中起作用<<<18,New>>>。
外形
含柠檬酸钠缓冲盐的冻干粉
其他说明
在具有3-磷酸甘油酸磷酸激酶的偶联系统中，在 pH 7.6、25℃ 条件下，一单位每分钟可将 1.0μmole的3-磷酸甘油酯减少为D-甘油醛3-磷酸。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
高风险级别生物产品--人源产品
此项目有
Qiao Liu et al.
Acta crystallographica. Section F, Structural biology and crystallization communications, 68(Pt 8), 978-980 (2012-08-08)
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is an important enzyme in the glycolytic pathway. In addition to its conventional metabolic role, GAPDH has been identified to possess diverse cellular functions. In this study, glyceraldehyde-3-phosphate dehydrogenase 3, the third isoform of GAPDH from Saccharomyces
Soya S Sam et al.
Pathology, research and practice, 208(12), 705-707 (2012-10-13)
Isolation of DNA from formalin-fixed, paraffin-embedded (FFPE) tissue remains a laborious task for clinical laboratories and researchers who need to screen several samples for genetic variants. The objective of this study was to evaluate DNA isolation methods from FFPE tissues
Anne Gürtler et al.
Analytical biochemistry, 433(2), 105-111 (2012-10-23)
Western blots are used to specifically measure the relative quantities of proteins of interest in complex biological samples. Quantitative measurements can be subject to error due to process inconsistencies such as uneven protein transfer to the membrane. These non-sample-related variations
Michele Salemi et al.
Tumori, 98(3), 86e-88e (2012-07-25)
Head and neck squamous cell carcinoma (HNSCC) is one of the most common cancers in the world. Risk factors for this cancer include tobacco and alcohol use, ultraviolet light exposure, and viral infection. Parkinson's disease is one of the most
Shunqing Liang et al.
Veterinary immunology and immunopathology, 150(3-4), 198-205 (2012-10-23)
Edwardsiella tarda is a Gram-negative pathogen which causes systemic infection in turbot. The increasing frequency of edwardsiellosis in turbot farming has stressed the need to understand the immune responses of fish, for the further development of prevention and control strategies.
商品
本页面介绍了一篇有关瓦博格效应的文章，以及其如何能够在正常氧气水平下，增强肿瘤细胞中葡萄糖向乳酸的转化。Otto Heinrich Warburg在1924年证明，癌细胞显示出对糖酵解的依赖性增加，以满足他们的能量需求，无论是否有充足的氧气存在。
Warburg effect enhances glucose to lactate conversion in tumor cells, regardless of oxygen levels; impacting cancer metabolism since 1924.
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