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Merck
CN

G6646

Growth Hormone Releasing Factor rat

≥95% (HPLC), powder, synthetic

别名:

GRF

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关于此项目

经验公式(希尔记法):
C225H361N77O66S
化学文摘社编号:
分子量:
5232.82
UNSPSC Code:
12352200
MDL number:
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InChI key

ORNDKVCWLUZAQL-FOWIMTFFSA-N

biological source

synthetic

assay

≥95% (HPLC)

form

powder

composition

Peptide content, ~70%

UniProt accession no.

storage temp.

−20°C

Gene Information

rat ... Ghrh(29446)

Biochem/physiol Actions

Hypothalamic peptide that stimulates release of somatotropin from anterior pituitary

存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

新产品
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历史批次信息供参考:

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J Kraicer et al.
Canadian journal of physiology and pharmacology, 69(2), 181-184 (1991-02-01)
The purpose of this study was to characterize the biological activity of the synthetic rat growth hormone releasing factor analogue rGRF(1-29)NH2 and to compare its action on growth hormone (GH) release to that of authentic rGRF(1-43)OH. We first compared the
L G Frigeri et al.
Endocrinology, 122(6), 2940-2945 (1988-06-01)
Treatment of obese yellow Avy/A mice with the human GH (hGH) peptide hGH-(1-43) enhanced the in vitro sensitivity of their adipose tissue to insulin. Insulin-stimulated glucose oxidation, as determined by measurement of 14CO2 production, was enhanced 106% after administration of
T Audhya et al.
Proceedings of the National Academy of Sciences of the United States of America, 82(9), 2970-2974 (1985-05-01)
Polyclonal antibodies to synthetic human pancreatic growth hormone-releasing factor [hpGRF(1-44)NH2] and rat hypothalamic growth hormone-releasing factor [rhGRF(1-43)OH] were produced in rabbits by injecting these weak immunogens, coupled to thyroglobulin and emulsified with complete Freund's adjuvant in the presence of activated
N Deslauriers et al.
Regulatory peptides, 20(3), 261-271 (1988-03-01)
We studied the effect of rat growth hormone-releasing factor-(1-43) acid, rGRF(1-43)OH, on the long-term secretion of rat growth hormone (rGH) in dispersed primary cultured cells of rat anterior pituitaries over a period of 7 days or longer. Results of the
J Spiess et al.
Nature, 303(5917), 532-535 (1983-06-09)
The importance of the hypothalamus in the regulation of growth hormone (GH) secretion from the adenohypophysis has been supported by experimental and clinical evidence. It has been observed that GH secretion is in part controlled by hypothalamic GH release-inhibiting factors

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