G6649
染料木黄酮
≥98% (HPLC), powder, tyrosine protein kinase inhibitor
别名:
4′,5,7-三羟基异黄酮, 5,7-二羟基-3-（4-羟基苯基）-4H-1-苯并吡喃-4-酮
选择尺寸
关于此项目
产品名称
染料木黄酮, synthetic, ≥98% (HPLC), powder
InChI key
TZBJGXHYKVUXJN-UHFFFAOYSA-N
InChI
1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,16-18H
SMILES string
Oc1ccc(cc1)C2=COc3cc(O)cc(O)c3C2=O
biological source
synthetic
assay
≥98% (HPLC)
form
powder
color
off-white to yellow
mp
297.0-298.0 °C
solubility
DMSO: soluble
ethanol: soluble
storage temp.
−20°C
Quality Level
Gene Information
human ... AKT1(207), CYP19A1(1588), EGFR(1956), ESR1(2099), ESR2(2100)
mouse ... Esr1(13982), Hexa(15211)
rat ... Adora1(29290), Adora2a(25369), Ar(24208)
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Application
- 用作评估雌激素活性的试验化合物
- 用作雌激素配体，以进行一致的报告基因活化试验，还用于检验染料木黄素与hER的结合β
- 用作内吞抑制剂，检验内吞晚期，溶酶体上的牛血清白蛋白（AGE-BSA）糖基化末端可能的作用
Biochem/physiol Actions
Features and Benefits
General description
Preparation Note
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type N95 (US)
商品
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