G6761
甘氨酸 钠盐 水合物
synthetic (organic), ≥99% (HPLC), immune function, metabolism, growth and development regulator, powder
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关于此项目
线性分子式:
H2NCH2CO2Na · xH2O
化学文摘社编号:
分子量:
97.05 (anhydrous basis)
MDL编号:
UNSPSC代码:
12352209
eCl@ss:
32160406
PubChem化学物质编号:
NACRES:
NA.77
产品名称
甘氨酸 钠盐 水合物, ≥99% (HPLC)
生物来源
synthetic (organic)
质量水平
方案
≥99% (HPLC)
表单
powder
分子量
97.05 g/mol (anhydrous basis)
技术
electrophoresis: suitable
mp
197-201 °C (lit.)
SMILES字符串
[Na+].[H]O[H].NCC([O-])=O
InChI
1S/C2H5NO2.Na.H2O/c3-1-2(4)5;;/h1,3H2,(H,4,5);;1H2/q;+1;/p-1
InChI key
CIJQGPVMMRXSQW-UHFFFAOYSA-M
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相关类别
一般描述
Research area: Neuroscience
Glycine is a simple non-essential amino acidIt is synthesized from choline, threonine and serine. It serves as a precursor for porphyrins, purines, glutathione and creatine.
Glycine is a simple non-essential amino acidIt is synthesized from choline, threonine and serine. It serves as a precursor for porphyrins, purines, glutathione and creatine.
应用
Glycine sodium salt hydrate has been used as a component of buffer for homogenization of whole muscle for protein extraction and in electrophoresis buffer. It has also been used as a neurotransmitter in immunohistochemical staining of Zebrafish spinal cord sections.
生化/生理作用
Glycine serves as a neurotransmitter in the central nervous system. It aids in increasing the quality of sleep and neurological functions. It is essential for the regulation immune function, metabolism, growth and development. Glycine modulates intracellular Ca2+ levels and cytokines production. Studies have shown that glycine treatment effectively prevents organ transplantation failure by mitigating ischemia reperfusion injury caused by cold ischemic storage. Additionally, glycine treatment also enhances graft function during transplantation. A reduction in glycine levels is observed in obesity, type 2 diabetes (T2DM), and non-alcoholic fatty liver disease (NAFLDs). Glycine is degraded to serine by glycine serine hydroxymethyltransferase 1 in cytoplasm.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Phylogenetic relationships among five marine Catfish species (Pisces: Ariidae) from Mexico
Tenorio-Colin G, et al.
Hidrobiologica, 20(3), 266-274 (2010)
Complementary expression of calcium binding proteins delineates the functional organization of the locomotor network
Berg EM, et al.
Brain Structure &Amp; Function, 223(5), 2181-2196 (2018)
Multifarious Beneficial Effect of Nonessential Amino Acid, Glycine: A Review
Razak MA, et al.
Oxidative Medicine and Cellular Longevity (2017)
J W Johnson et al.
Nature, 325(6104), 529-531 (1987-02-05)
Transmitters mediating 'fast' synaptic processes in the vertebrate central nervous system are commonly placed in two separate categories that are believed to exhibit no interaction at the receptor level. The 'inhibitory transmitters' (such as glycine and GABA) are considered to
Glycine Metabolism and Its Alterations in Obesity and Metabolic Diseases
Alves A, et al.
Nutrients, 11(6), 1356-1356 (2019)
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