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Merck
CN

G6776

染料木黄酮

From Glycine max (soybean), ~98% (HPLC), tyrosine protein kinase inhibitor, powder

别名:

4′,5,7-三羟基异黄酮, 5,7-二羟基-3-（4-羟基苯基）-4H-1-苯并吡喃-4-酮

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关于此项目

经验公式（希尔记法）:
C15H10O5
化学文摘社编号:
446-72-0
分子量:
270.24
NACRES:
NA.77
PubChem Substance ID:
24895273
UNSPSC Code:
12352200
EC Number:
207-174-9
MDL number:
MFCD00016952
Beilstein/REAXYS Number:
263823

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产品名称

染料木黄酮, from Glycine max (soybean), ~98% (HPLC)

InChI key

TZBJGXHYKVUXJN-UHFFFAOYSA-N

InChI

1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,16-18H

SMILES string

Oc1ccc(cc1)C2=COc3cc(O)cc(O)c3C2=O

biological source

Glycine max (soybean)

assay

~98% (HPLC)

form

powder

mp

>280 °C

solubility

DMSO: soluble
ethanol: soluble

storage temp.

−20°C

Quality Level

200

Gene Information

human ... AKT1(207), CYP19A1(1588), EGFR(1956), ESR1(2099), ESR2(2100)
mouse ... Esr1(13982), Hexa(15211)
rat ... Adora1(29290), Adora2a(25369), Ar(24208)

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相关类别

Application

金雀异黄素已被用作：
  • 作为抗癌剂用于测试其在宫颈腺癌细胞中的细胞毒性
  • 作为多酚用于测试其对精子线粒体中活性氧的作用
  • 测试其对紫外照射下皮肤和瘢痕疙瘩成纤维细胞的自由基清除作用

Biochem/physiol Actions

酪氨酸蛋白激酶抑制剂; 在其他蛋白激酶反应中，ATP的竞争性抑制剂。 抗血管生成剂，可下调参与控制血管生成的基因的转录。
金雀异黄素具有抗氧化功能，并可有效淬灭活性氧。它有益于人体健康。

Features and Benefits

该化合物是《受体分类及信号转导手册》上Met页面上的特色化合物。想要浏览手册的其他页面， 请单击此处。

General description

金雀异黄素是来自大豆的异黄酮营养保健品，同时也是一种植物雌激素。它来源于染料木苷。

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000486021
0000486021
0000458669
0000458669
0000404420

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膳食抗氧化剂

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